Paraneoplastic glomerulopathy in a case of collecting duct renal cell carcinoma

Srikanth Prasad Devarsetty, Dharshan Rangaswamy, Shailaja Bhat, Shankar Prasad Nagaraju, Ravindra Prabhu Attur

Research output: Contribution to journalArticle

Abstract

Paraneoplasticglomerulopathy has been described in established cases of the solid tumors of lung, gastrointestinal system, breast, etc., and rarely in patients with Renal Cell Carcinoma (RCC). Studies on secondary glomerular diseases have described a higher incidence of IgA nephropathy in patients with RCC compared to membranous glomerulopathy, which are commonly reported in malignancies of the lung and gastrointestinal tract. Collecting Duct Carcinoma (CDC), a rare high grade adenocarcinoma accounts for <1% of all renal malignancies. It arises from the cells of the collecting ducts of Bellini.We report a case of an elderly male who was diagnosed to have a disseminated CDC during his evaluation for nephrotic syndrome. Renal biopsy was suggestive of a secondary Membranous glomerulonephropathy.

Original languageEnglish
Pages (from-to)OD03-OD04
JournalJournal of Clinical and Diagnostic Research
Volume11
Issue number2
DOIs
Publication statusPublished - 01-02-2017

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Renal Cell Carcinoma
Ducts
Cells
Membranous Glomerulonephritis
Biopsy
Kidney
Neoplasms
Lung
Immunoglobulin A
Tumors
Nephrotic Syndrome
Gastrointestinal Tract
Adenocarcinoma
Breast
Incidence

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

Devarsetty, Srikanth Prasad ; Rangaswamy, Dharshan ; Bhat, Shailaja ; Nagaraju, Shankar Prasad ; Attur, Ravindra Prabhu. / Paraneoplastic glomerulopathy in a case of collecting duct renal cell carcinoma. In: Journal of Clinical and Diagnostic Research. 2017 ; Vol. 11, No. 2. pp. OD03-OD04.
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Paraneoplastic glomerulopathy in a case of collecting duct renal cell carcinoma. / Devarsetty, Srikanth Prasad; Rangaswamy, Dharshan; Bhat, Shailaja; Nagaraju, Shankar Prasad; Attur, Ravindra Prabhu.

In: Journal of Clinical and Diagnostic Research, Vol. 11, No. 2, 01.02.2017, p. OD03-OD04.

Research output: Contribution to journalArticle

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AU - Devarsetty, Srikanth Prasad

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AU - Attur, Ravindra Prabhu

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AB - Paraneoplasticglomerulopathy has been described in established cases of the solid tumors of lung, gastrointestinal system, breast, etc., and rarely in patients with Renal Cell Carcinoma (RCC). Studies on secondary glomerular diseases have described a higher incidence of IgA nephropathy in patients with RCC compared to membranous glomerulopathy, which are commonly reported in malignancies of the lung and gastrointestinal tract. Collecting Duct Carcinoma (CDC), a rare high grade adenocarcinoma accounts for <1% of all renal malignancies. It arises from the cells of the collecting ducts of Bellini.We report a case of an elderly male who was diagnosed to have a disseminated CDC during his evaluation for nephrotic syndrome. Renal biopsy was suggestive of a secondary Membranous glomerulonephropathy.

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