Parental transmission of type 2 diabetes mellitus among patients attending a tertiary care hospital

Manasi Gupta, Asif Iqbal, Suma Nair, Muralidhar Varma, Sudha Vidyasagar

Research output: Contribution to journalArticle

Abstract

Problem considered: Type 2 Diabetes Mellitus is a heritable condition. Some studies suggest a strong maternal association while others claim paternal transmission of diabetes to be more significant. The present study was aimed at identifying the role of parental transmission in Type 2 diabetic patients with family history of diabetes. Methods: This was a cross-sectional study carried out among individuals diagnosed with Type 2 Diabetes Mellitus (DM) and having a family history of the same attending the General Medicine OPD in a tertiary care hospital. Consenting consecutive patients fulfilling the inclusion criteria were enrolled into the study. Demographic characteristics, age at onset of Type 2 Diabetes and parental history of the disease were obtained in detail. Results: Of the 174 participants enrolled into the study nearly 66% were males. Maternal history of DM (65%) was more commonly observed as compared to paternal history (57%) and nearly 23% had a history of both parents being diabetic. Fifty two percent gave a sibling history of type 2 DM. Siblings of patients with affected mothers had a greater likelihood of diabetes (77.8%) than those with affected fathers (51%) (P = 0.001). More males had a brother who was diabetic (66%), likewise more females had a sister who was diabetic (55%). Conclusion: Maternal inheritance of DM appears to be more common and there is a significant association of type 2 diabetes among siblings of patients with affected mothers. This apparent association is an area that needs to be explored further.

Original languageEnglish
Pages (from-to)99-102
Number of pages4
JournalClinical Epidemiology and Global Health
Volume3
Issue number2
DOIs
Publication statusPublished - 01-08-2015

Fingerprint

Tertiary Healthcare
Tertiary Care Centers
Type 2 Diabetes Mellitus
Siblings
Mothers
Diabetes Mellitus
Age of Onset
Fathers
Cross-Sectional Studies
Parents
History
Medicine
Demography

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases

Cite this

@article{d796c0a2e048439994a095221c1379cc,
title = "Parental transmission of type 2 diabetes mellitus among patients attending a tertiary care hospital",
abstract = "Problem considered: Type 2 Diabetes Mellitus is a heritable condition. Some studies suggest a strong maternal association while others claim paternal transmission of diabetes to be more significant. The present study was aimed at identifying the role of parental transmission in Type 2 diabetic patients with family history of diabetes. Methods: This was a cross-sectional study carried out among individuals diagnosed with Type 2 Diabetes Mellitus (DM) and having a family history of the same attending the General Medicine OPD in a tertiary care hospital. Consenting consecutive patients fulfilling the inclusion criteria were enrolled into the study. Demographic characteristics, age at onset of Type 2 Diabetes and parental history of the disease were obtained in detail. Results: Of the 174 participants enrolled into the study nearly 66{\%} were males. Maternal history of DM (65{\%}) was more commonly observed as compared to paternal history (57{\%}) and nearly 23{\%} had a history of both parents being diabetic. Fifty two percent gave a sibling history of type 2 DM. Siblings of patients with affected mothers had a greater likelihood of diabetes (77.8{\%}) than those with affected fathers (51{\%}) (P = 0.001). More males had a brother who was diabetic (66{\%}), likewise more females had a sister who was diabetic (55{\%}). Conclusion: Maternal inheritance of DM appears to be more common and there is a significant association of type 2 diabetes among siblings of patients with affected mothers. This apparent association is an area that needs to be explored further.",
author = "Manasi Gupta and Asif Iqbal and Suma Nair and Muralidhar Varma and Sudha Vidyasagar",
year = "2015",
month = "8",
day = "1",
doi = "10.1016/j.cegh.2015.04.002",
language = "English",
volume = "3",
pages = "99--102",
journal = "Clinical Epidemiology and Global Health",
issn = "2213-3984",
publisher = "Elsevier BV",
number = "2",

}

Parental transmission of type 2 diabetes mellitus among patients attending a tertiary care hospital. / Gupta, Manasi; Iqbal, Asif; Nair, Suma; Varma, Muralidhar; Vidyasagar, Sudha.

In: Clinical Epidemiology and Global Health, Vol. 3, No. 2, 01.08.2015, p. 99-102.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Parental transmission of type 2 diabetes mellitus among patients attending a tertiary care hospital

AU - Gupta, Manasi

AU - Iqbal, Asif

AU - Nair, Suma

AU - Varma, Muralidhar

AU - Vidyasagar, Sudha

PY - 2015/8/1

Y1 - 2015/8/1

N2 - Problem considered: Type 2 Diabetes Mellitus is a heritable condition. Some studies suggest a strong maternal association while others claim paternal transmission of diabetes to be more significant. The present study was aimed at identifying the role of parental transmission in Type 2 diabetic patients with family history of diabetes. Methods: This was a cross-sectional study carried out among individuals diagnosed with Type 2 Diabetes Mellitus (DM) and having a family history of the same attending the General Medicine OPD in a tertiary care hospital. Consenting consecutive patients fulfilling the inclusion criteria were enrolled into the study. Demographic characteristics, age at onset of Type 2 Diabetes and parental history of the disease were obtained in detail. Results: Of the 174 participants enrolled into the study nearly 66% were males. Maternal history of DM (65%) was more commonly observed as compared to paternal history (57%) and nearly 23% had a history of both parents being diabetic. Fifty two percent gave a sibling history of type 2 DM. Siblings of patients with affected mothers had a greater likelihood of diabetes (77.8%) than those with affected fathers (51%) (P = 0.001). More males had a brother who was diabetic (66%), likewise more females had a sister who was diabetic (55%). Conclusion: Maternal inheritance of DM appears to be more common and there is a significant association of type 2 diabetes among siblings of patients with affected mothers. This apparent association is an area that needs to be explored further.

AB - Problem considered: Type 2 Diabetes Mellitus is a heritable condition. Some studies suggest a strong maternal association while others claim paternal transmission of diabetes to be more significant. The present study was aimed at identifying the role of parental transmission in Type 2 diabetic patients with family history of diabetes. Methods: This was a cross-sectional study carried out among individuals diagnosed with Type 2 Diabetes Mellitus (DM) and having a family history of the same attending the General Medicine OPD in a tertiary care hospital. Consenting consecutive patients fulfilling the inclusion criteria were enrolled into the study. Demographic characteristics, age at onset of Type 2 Diabetes and parental history of the disease were obtained in detail. Results: Of the 174 participants enrolled into the study nearly 66% were males. Maternal history of DM (65%) was more commonly observed as compared to paternal history (57%) and nearly 23% had a history of both parents being diabetic. Fifty two percent gave a sibling history of type 2 DM. Siblings of patients with affected mothers had a greater likelihood of diabetes (77.8%) than those with affected fathers (51%) (P = 0.001). More males had a brother who was diabetic (66%), likewise more females had a sister who was diabetic (55%). Conclusion: Maternal inheritance of DM appears to be more common and there is a significant association of type 2 diabetes among siblings of patients with affected mothers. This apparent association is an area that needs to be explored further.

UR - http://www.scopus.com/inward/record.url?scp=84964194328&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964194328&partnerID=8YFLogxK

U2 - 10.1016/j.cegh.2015.04.002

DO - 10.1016/j.cegh.2015.04.002

M3 - Article

AN - SCOPUS:84964194328

VL - 3

SP - 99

EP - 102

JO - Clinical Epidemiology and Global Health

JF - Clinical Epidemiology and Global Health

SN - 2213-3984

IS - 2

ER -