Peritonitis due to Neisseria mucosa in an adolescent receiving peritoneal dialysis

A. K. Shetty, S. K. Nagaraj, W. B. Lorentz, M. Bitzan

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10 Citations (Scopus)

Abstract

Neisseria mucosa is part of the normal nasopharyngeal flora and rarely pathogenic in humans. Reports of serious infections associated with this pathogen are very unusual. A 17-year-old boy with end-stage renal disease due to IgA nephropathy presented with acute, spontaneous, symptomatic peritoneal, dialysis-associated peritonitis without reported break in sterility or PD catheter exit site infection. β-lactamase-negative N. mucosa was isolated from the dialysate effluent. Intraperitoneal antibiotic treatment with cephalothin/gentamicin for 5 days and subsequent ceftriaxone led to complete resolution of the infection. This case demonstrates that "non- pathogenic" Neisseria species can cause clinically severe peritonitis with high intraperitoneal neutrophil counts, elevated C-reactive protein levels in the peritoneal effluent (in the presented case, 27,600/μl and 3.6 mg/l, respectively) and impaired peritoneal membrane transport function. To our knowledge, this is the first case of N. mucosa peritonitis complicating chronic peritoneal dialysis in an adolescent patient.

Original languageEnglish
Pages (from-to)390-392
Number of pages3
JournalInfection
Volume33
Issue number5-6
DOIs
Publication statusPublished - 01-10-2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Immunology

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    Shetty, A. K., Nagaraj, S. K., Lorentz, W. B., & Bitzan, M. (2005). Peritonitis due to Neisseria mucosa in an adolescent receiving peritoneal dialysis. Infection, 33(5-6), 390-392. https://doi.org/10.1007/s15010-005-5074-4