Phenolic glucosides from Flacourtia indica

S. Madan, S.T. Pannakal, S. Ganapaty, G.N. Singh, Y. Kumar

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

A new phenolic glucoside, (rel)-2-(4′,6′-dibenzoyl-β- glucopyranosyloxy)-7-(1́-hydroxy-2́-ethoxy-6́-acetyloxy-3- oxocyclohex-4-enoyl)-benzyl alcohol (Flacourticin) (1) and the known, 2-(4′,6′-dibenzoyl-β-glucopyranosyl)-5-hydroxy benzyl alcohol (4′-benzoylpoliothrysoside) (2) together with the new, (2E)-heptyl-3-(3,4-dihydroxyphenyl) acrylate (3), (+)-catechin (4) and sitosterol-β-D-glucoside were isolated from Flacourtia indica. Their structures were assigned on the basis of 1D, 2D-NMR and as well by analysis of the LC-ESIMS data. The isolated compounds (1-4) were evaluated for α,α-diphenyl-β-picrylhydrazyl (DPPH) radical scavenging activity, and 3 was found to be two-fold less potent, with an IC50 =12.01 μg/mL, compared to the positive control, Rutin, (IC50 = 5.83 μg/mL).
Original languageEnglish
Pages (from-to)381-384
Number of pages4
JournalNatural Product Communications
Volume4
Issue number3
DOIs
Publication statusPublished - 2009

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    Madan, S., Pannakal, S. T., Ganapaty, S., Singh, G. N., & Kumar, Y. (2009). Phenolic glucosides from Flacourtia indica. Natural Product Communications, 4(3), 381-384. https://doi.org/10.1021/jf010678d