Abstract

Pilocarpine HCl and β-cyclodextrin kneading complex was entrapped in niosomes followed by dispersion in hydroxypropylmethylcellulose gel. In-vitro release studies showed that the product exhibited slow release compared with release of plain drug. In-vivo studies also showed miotic action for a longer duration indicating the slow and sustained release of the niosome-entrapped complex.

Original languageEnglish
Pages (from-to)383-386
Number of pages4
JournalPharmaceutical Sciences
Volume3
Issue number8
Publication statusPublished - 1997

Fingerprint

Pilocarpine
Cyclodextrins
Liposomes
Miotics
Gels
In Vitro Techniques
Drug Liberation
Hypromellose Derivatives

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

Sheena, I. P., Singh, U. V., Aithal, K. S., & Udupa, N. (1997). Pilocarpine β-cyclodextrin complexation and niosomal entrapment. Pharmaceutical Sciences, 3(8), 383-386.
Sheena, I. P. ; Singh, U. V. ; Aithal, K. S. ; Udupa, N. / Pilocarpine β-cyclodextrin complexation and niosomal entrapment. In: Pharmaceutical Sciences. 1997 ; Vol. 3, No. 8. pp. 383-386.
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abstract = "Pilocarpine HCl and β-cyclodextrin kneading complex was entrapped in niosomes followed by dispersion in hydroxypropylmethylcellulose gel. In-vitro release studies showed that the product exhibited slow release compared with release of plain drug. In-vivo studies also showed miotic action for a longer duration indicating the slow and sustained release of the niosome-entrapped complex.",
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Sheena, IP, Singh, UV, Aithal, KS & Udupa, N 1997, 'Pilocarpine β-cyclodextrin complexation and niosomal entrapment', Pharmaceutical Sciences, vol. 3, no. 8, pp. 383-386.

Pilocarpine β-cyclodextrin complexation and niosomal entrapment. / Sheena, I. P.; Singh, U. V.; Aithal, K. S.; Udupa, N.

In: Pharmaceutical Sciences, Vol. 3, No. 8, 1997, p. 383-386.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Pilocarpine β-cyclodextrin complexation and niosomal entrapment

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AU - Singh, U. V.

AU - Aithal, K. S.

AU - Udupa, N.

PY - 1997

Y1 - 1997

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VL - 3

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