Abstract

Pilocarpine HCl and β-cyclodextrin kneading complex was entrapped in niosomes followed by dispersion in hydroxypropylmethylcellulose gel. In-vitro release studies showed that the product exhibited slow release compared with release of plain drug. In-vivo studies also showed miotic action for a longer duration indicating the slow and sustained release of the niosome-entrapped complex.

Original languageEnglish
Pages (from-to)383-386
Number of pages4
JournalPharmaceutical Sciences
Volume3
Issue number8
Publication statusPublished - 1997

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

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    Sheena, I. P., Singh, U. V., Aithal, K. S., & Udupa, N. (1997). Pilocarpine β-cyclodextrin complexation and niosomal entrapment. Pharmaceutical Sciences, 3(8), 383-386.