Plasma antioxidant vitamins and lipid peroxidation products in pregnancy induced hypertension

Gayatri M. Rao, P. Sumita, M. Roshni, M. N. Ashtagimatt

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

It has been suggested that antioxidant systems are impaired in pregnancy induced hypertension and hence patients are exposed to oxidative stress. In order to investigate the relationship between lipid peroxidation and certain antioxidant parameters in blood of pregnancy induced hypertension (PIH) cases, 25 normotensive and 23 PIH samples were studied. In the present study, thiobarbituric acid reactive substances showed a tendency to increase, however the increase remained statistically insignificant. Plasma ascorbic acid level remained unaltered and Vitamin E showed a tendency to increase in the study group. The findings implicate oxidative stress in the disease and cite the biochemical rationale for clinical trials of antioxidants to prevent and treat pregnancy induced hypertension.

Original languageEnglish
Pages (from-to)198-200
Number of pages3
JournalIndian Journal of Clinical Biochemistry
Volume20
Issue number1
DOIs
Publication statusPublished - 01-01-2005

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

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