Plasma protein oxidation and total antioxidant power in premenstrual syndrome

Eans Tara Tuladhar, Anjali Rao

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective: To explore whether oxidative stress has any role in premenstrual syndrome (PMS). Methods: Female volunteers suffering from PMS, in the age group of 20-24 years were compared to their asymptomatic normomennorhoeic counterparts in follicular phase and late luteal phase for ferric reducing antioxidant power of plasma (FRAP), plasma protein thiols (PPT) and protein carbonyls (PPC) levels. Results: There was no significant change in FRAP and PPC levels in controls and PMS groups but PPT decreased significantly in luteal phase of PMS (P<0.05) when compared to follicular phase. Conclusions: Estrogen and progesterone, might be responsible for a healthy antioxidant profile in PMS. However, a marked decrease in PPT in luteal phase of PMS group may be due to pro-oxidant nature of estrogen-active in this phase of PMS leading to consumption of the sacrificial antioxidant-protein thiol.

Original languageEnglish
Pages (from-to)237-240
Number of pages4
JournalAsian Pacific Journal of Tropical Medicine
Volume3
Issue number3
DOIs
Publication statusPublished - 01-03-2010
Externally publishedYes

Fingerprint

Premenstrual Syndrome
Blood Proteins
Antioxidants
Sulfhydryl Compounds
Luteal Phase
Follicular Phase
Estrogens
Progesterone
Volunteers
Reactive Oxygen Species
Proteins
Oxidative Stress
Age Groups

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{181f52b17c73497fa346a7d0ecfff457,
title = "Plasma protein oxidation and total antioxidant power in premenstrual syndrome",
abstract = "Objective: To explore whether oxidative stress has any role in premenstrual syndrome (PMS). Methods: Female volunteers suffering from PMS, in the age group of 20-24 years were compared to their asymptomatic normomennorhoeic counterparts in follicular phase and late luteal phase for ferric reducing antioxidant power of plasma (FRAP), plasma protein thiols (PPT) and protein carbonyls (PPC) levels. Results: There was no significant change in FRAP and PPC levels in controls and PMS groups but PPT decreased significantly in luteal phase of PMS (P<0.05) when compared to follicular phase. Conclusions: Estrogen and progesterone, might be responsible for a healthy antioxidant profile in PMS. However, a marked decrease in PPT in luteal phase of PMS group may be due to pro-oxidant nature of estrogen-active in this phase of PMS leading to consumption of the sacrificial antioxidant-protein thiol.",
author = "Tuladhar, {Eans Tara} and Anjali Rao",
year = "2010",
month = "3",
day = "1",
doi = "10.1016/S1995-7645(10)60017-X",
language = "English",
volume = "3",
pages = "237--240",
journal = "Asian Pacific Journal of Tropical Medicine",
issn = "1995-7645",
publisher = "Elsevier (Singapore) Pte Ltd",
number = "3",

}

Plasma protein oxidation and total antioxidant power in premenstrual syndrome. / Tuladhar, Eans Tara; Rao, Anjali.

In: Asian Pacific Journal of Tropical Medicine, Vol. 3, No. 3, 01.03.2010, p. 237-240.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Plasma protein oxidation and total antioxidant power in premenstrual syndrome

AU - Tuladhar, Eans Tara

AU - Rao, Anjali

PY - 2010/3/1

Y1 - 2010/3/1

N2 - Objective: To explore whether oxidative stress has any role in premenstrual syndrome (PMS). Methods: Female volunteers suffering from PMS, in the age group of 20-24 years were compared to their asymptomatic normomennorhoeic counterparts in follicular phase and late luteal phase for ferric reducing antioxidant power of plasma (FRAP), plasma protein thiols (PPT) and protein carbonyls (PPC) levels. Results: There was no significant change in FRAP and PPC levels in controls and PMS groups but PPT decreased significantly in luteal phase of PMS (P<0.05) when compared to follicular phase. Conclusions: Estrogen and progesterone, might be responsible for a healthy antioxidant profile in PMS. However, a marked decrease in PPT in luteal phase of PMS group may be due to pro-oxidant nature of estrogen-active in this phase of PMS leading to consumption of the sacrificial antioxidant-protein thiol.

AB - Objective: To explore whether oxidative stress has any role in premenstrual syndrome (PMS). Methods: Female volunteers suffering from PMS, in the age group of 20-24 years were compared to their asymptomatic normomennorhoeic counterparts in follicular phase and late luteal phase for ferric reducing antioxidant power of plasma (FRAP), plasma protein thiols (PPT) and protein carbonyls (PPC) levels. Results: There was no significant change in FRAP and PPC levels in controls and PMS groups but PPT decreased significantly in luteal phase of PMS (P<0.05) when compared to follicular phase. Conclusions: Estrogen and progesterone, might be responsible for a healthy antioxidant profile in PMS. However, a marked decrease in PPT in luteal phase of PMS group may be due to pro-oxidant nature of estrogen-active in this phase of PMS leading to consumption of the sacrificial antioxidant-protein thiol.

UR - http://www.scopus.com/inward/record.url?scp=77950657801&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950657801&partnerID=8YFLogxK

U2 - 10.1016/S1995-7645(10)60017-X

DO - 10.1016/S1995-7645(10)60017-X

M3 - Article

AN - SCOPUS:77950657801

VL - 3

SP - 237

EP - 240

JO - Asian Pacific Journal of Tropical Medicine

JF - Asian Pacific Journal of Tropical Medicine

SN - 1995-7645

IS - 3

ER -