PONV: Comparison of TIVA with propofol versus inhalataion anaesthesia

Patients & Methods: Sixty ASA grade 1 and II patients in the age group of 15-45 years were studied in two equal groups. Group I (P/O ₂) received propofol for anaesthesia induction and maintained on propofol infusion and oxygen. Group II (P/N ₂O) also received propofol for induction of anaesthesia and maintained on 60% Nitrous oxide in oxygen and Halothane. Results: Patients in P/O ₂: group had no emetic episodes (0%) in comparison to 16.7% in P/N ₂O group during early post operative period (0-4 hours). It was also observed that 3.3% of the patients in P/O ₂ group had emetic episodes compared to 6.7% in P/N ₂O group during late post operative period (4-24 hours). The results were analysed using student unpaired t test, Mann-Whitney U test, Chi-square test, Fisher's exact test and Gaussian test. Conclusion: We conclude that TIVA with propofol results in significant reduction in PONV compared to inhalation anaesthesia (N ₂O-O2-Halothane).