Patients & Methods: Sixty ASA grade 1 and II patients in the age group of 15-45 years were studied in two equal groups. Group I (P/O 2) received propofol for anaesthesia induction and maintained on propofol infusion and oxygen. Group II (P/N 2O) also received propofol for induction of anaesthesia and maintained on 60% Nitrous oxide in oxygen and Halothane. Results: Patients in P/O 2: group had no emetic episodes (0%) in comparison to 16.7% in P/N 2O group during early post operative period (0-4 hours). It was also observed that 3.3% of the patients in P/O 2 group had emetic episodes compared to 6.7% in P/N 2O group during late post operative period (4-24 hours). The results were analysed using student unpaired t test, Mann-Whitney U test, Chi-square test, Fisher's exact test and Gaussian test. Conclusion: We conclude that TIVA with propofol results in significant reduction in PONV compared to inhalation anaesthesia (N 2O-O2-Halothane).
|Number of pages||4|
|Journal||Journal of Anaesthesiology Clinical Pharmacology|
|Publication status||Published - 01-10-2007|
All Science Journal Classification (ASJC) codes
- Pharmacology (medical)
- Anesthesiology and Pain Medicine
- Pharmacology, Toxicology and Pharmaceutics(all)