Poorly differentiated (insular) thyroid carcinoma arising in a long-standing colloid goitre: A cytological dilemma

Hema Kini, M. Nirupama, Aarathi Rau, Sumit Gupta, Alfred Augustine

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Poorly differentiated (insular) thyroid carcinoma (PDITC) is an uncommon thyroglobulin producing neoplasm intermediate in aggressiveness between well-differentiated carcinomas of follicular cell origin and undifferentiated anaplastic carcinoma. Its cytomorphological recognition is essential for planning surgery and subsequent management as it is known for its aggressive behavior, advanced stage at presentation, local recurrences and rapid dissemination. We report a case of PDITC arising in a long-standing goiter, in which presence of microfollicular structures and minimal necrosis resulted in difficulty in distinguishing it from a follicular neoplasm of thyroid.

Original languageEnglish
Pages (from-to)97-99
Number of pages3
JournalJournal of Cytology
Volume29
Issue number1
DOIs
Publication statusPublished - 01-01-2012

Fingerprint

Goiter
Colloids
Thyroid Neoplasms
Carcinoma
Thyroglobulin
Necrosis
Recurrence
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

Cite this

@article{db3429e95f23414292db0968f303a1c9,
title = "Poorly differentiated (insular) thyroid carcinoma arising in a long-standing colloid goitre: A cytological dilemma",
abstract = "Poorly differentiated (insular) thyroid carcinoma (PDITC) is an uncommon thyroglobulin producing neoplasm intermediate in aggressiveness between well-differentiated carcinomas of follicular cell origin and undifferentiated anaplastic carcinoma. Its cytomorphological recognition is essential for planning surgery and subsequent management as it is known for its aggressive behavior, advanced stage at presentation, local recurrences and rapid dissemination. We report a case of PDITC arising in a long-standing goiter, in which presence of microfollicular structures and minimal necrosis resulted in difficulty in distinguishing it from a follicular neoplasm of thyroid.",
author = "Hema Kini and M. Nirupama and Aarathi Rau and Sumit Gupta and Alfred Augustine",
year = "2012",
month = "1",
day = "1",
doi = "10.4103/0970-9371.93237",
language = "English",
volume = "29",
pages = "97--99",
journal = "Journal of Cytology",
issn = "0970-9371",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "1",

}

Poorly differentiated (insular) thyroid carcinoma arising in a long-standing colloid goitre : A cytological dilemma. / Kini, Hema; Nirupama, M.; Rau, Aarathi; Gupta, Sumit; Augustine, Alfred.

In: Journal of Cytology, Vol. 29, No. 1, 01.01.2012, p. 97-99.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Poorly differentiated (insular) thyroid carcinoma arising in a long-standing colloid goitre

T2 - A cytological dilemma

AU - Kini, Hema

AU - Nirupama, M.

AU - Rau, Aarathi

AU - Gupta, Sumit

AU - Augustine, Alfred

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Poorly differentiated (insular) thyroid carcinoma (PDITC) is an uncommon thyroglobulin producing neoplasm intermediate in aggressiveness between well-differentiated carcinomas of follicular cell origin and undifferentiated anaplastic carcinoma. Its cytomorphological recognition is essential for planning surgery and subsequent management as it is known for its aggressive behavior, advanced stage at presentation, local recurrences and rapid dissemination. We report a case of PDITC arising in a long-standing goiter, in which presence of microfollicular structures and minimal necrosis resulted in difficulty in distinguishing it from a follicular neoplasm of thyroid.

AB - Poorly differentiated (insular) thyroid carcinoma (PDITC) is an uncommon thyroglobulin producing neoplasm intermediate in aggressiveness between well-differentiated carcinomas of follicular cell origin and undifferentiated anaplastic carcinoma. Its cytomorphological recognition is essential for planning surgery and subsequent management as it is known for its aggressive behavior, advanced stage at presentation, local recurrences and rapid dissemination. We report a case of PDITC arising in a long-standing goiter, in which presence of microfollicular structures and minimal necrosis resulted in difficulty in distinguishing it from a follicular neoplasm of thyroid.

UR - http://www.scopus.com/inward/record.url?scp=84863243812&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863243812&partnerID=8YFLogxK

U2 - 10.4103/0970-9371.93237

DO - 10.4103/0970-9371.93237

M3 - Article

AN - SCOPUS:84863243812

VL - 29

SP - 97

EP - 99

JO - Journal of Cytology

JF - Journal of Cytology

SN - 0970-9371

IS - 1

ER -