Population norms for frequency doubling perimetry with uncorrected refractive error

Sathyamangalam Ve Ramesh, Ronnie George, Premal M. Soni, Lakshmanan Palaniappan, Prema Raju, Pradeep G. Paul, Sivarathinasami Ramsathish, Lingam Vijaya

Research output: Contribution to journalArticle

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Abstract

PURPOSE. To compare the effect of uncorrected refractive error on threshold estimation using frequency doubling perimetry (FDP) full-threshold N-30 with emmetropia among normal subjects. METHODS. One thousand two hundred ninety-nine subjects were enrolled from the Chennai Glaucoma Study, a population-based glaucoma prevalence study. Subjects underwent a comprehensive eye examination including the FDP full-threshold N-30 test. Normal subjects (with spherical equivalent refractive errors within ±7 D) with no other ocular pathology were stratified into six groups based on the degree of myopia and hyperopia and compared with age-matched emmetropic controls. A subset of 22 subjects with higher refractive errors was assessed for within-subject effect on FDP parameters. The following FDP parameters were compared: mean deviation, pattern standard deviation, central threshold (CT), mean sensitivity (MS), paracentral points (PA), and peripheral threshold. RESULTS. The one-way analysis of variance between all refractive error groups and emmetropes showed no statistically significant difference for the mean deviation (p = 0.1002) and pattern standard deviation (p = 0.4789). FDP parameters did not show a statistically significant difference for between and within-group comparisons. The variability of FDP sensitivity (derived from the 95% confidence interval range) as a proportion of the threshold range of the instrument was 31, 41, 46, and 41% for CT, MS, PA, and peripheral sensitivity, respectively, without spectacle correction and 29, 34, 36, and 35% for CT, MS, PA, and peripheral sensitivity, respectively, with correction. The mean CT, PA, and peripheral sensitivity show a decreasing trend from central to periphery in all the refractive error groups and a similar trend was noted in the emmetropic controls. CONCLUSION. Between-subject (uncorrected ammetropes and age-matched emmetropes) and within-subject comparisons showed no statistically significant differences in any of the FDP parameters or in the contrast sensitivity estimates between the central and peripheral test locations. This finding is likely due to the high within-subject variability of FDP.

Original languageEnglish
Pages (from-to)496-504
Number of pages9
JournalOptometry and Vision Science
Volume84
Issue number6
DOIs
Publication statusPublished - 01-06-2007

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Visual Field Tests
Refractive Errors
Population
Glaucoma
Emmetropia
Hyperopia
Contrast Sensitivity
Myopia
Analysis of Variance
Cross-Sectional Studies
Confidence Intervals
Pathology

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Optometry

Cite this

Ve Ramesh, Sathyamangalam ; George, Ronnie ; Soni, Premal M. ; Palaniappan, Lakshmanan ; Raju, Prema ; Paul, Pradeep G. ; Ramsathish, Sivarathinasami ; Vijaya, Lingam. / Population norms for frequency doubling perimetry with uncorrected refractive error. In: Optometry and Vision Science. 2007 ; Vol. 84, No. 6. pp. 496-504.
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title = "Population norms for frequency doubling perimetry with uncorrected refractive error",
abstract = "PURPOSE. To compare the effect of uncorrected refractive error on threshold estimation using frequency doubling perimetry (FDP) full-threshold N-30 with emmetropia among normal subjects. METHODS. One thousand two hundred ninety-nine subjects were enrolled from the Chennai Glaucoma Study, a population-based glaucoma prevalence study. Subjects underwent a comprehensive eye examination including the FDP full-threshold N-30 test. Normal subjects (with spherical equivalent refractive errors within ±7 D) with no other ocular pathology were stratified into six groups based on the degree of myopia and hyperopia and compared with age-matched emmetropic controls. A subset of 22 subjects with higher refractive errors was assessed for within-subject effect on FDP parameters. The following FDP parameters were compared: mean deviation, pattern standard deviation, central threshold (CT), mean sensitivity (MS), paracentral points (PA), and peripheral threshold. RESULTS. The one-way analysis of variance between all refractive error groups and emmetropes showed no statistically significant difference for the mean deviation (p = 0.1002) and pattern standard deviation (p = 0.4789). FDP parameters did not show a statistically significant difference for between and within-group comparisons. The variability of FDP sensitivity (derived from the 95{\%} confidence interval range) as a proportion of the threshold range of the instrument was 31, 41, 46, and 41{\%} for CT, MS, PA, and peripheral sensitivity, respectively, without spectacle correction and 29, 34, 36, and 35{\%} for CT, MS, PA, and peripheral sensitivity, respectively, with correction. The mean CT, PA, and peripheral sensitivity show a decreasing trend from central to periphery in all the refractive error groups and a similar trend was noted in the emmetropic controls. CONCLUSION. Between-subject (uncorrected ammetropes and age-matched emmetropes) and within-subject comparisons showed no statistically significant differences in any of the FDP parameters or in the contrast sensitivity estimates between the central and peripheral test locations. This finding is likely due to the high within-subject variability of FDP.",
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Ve Ramesh, S, George, R, Soni, PM, Palaniappan, L, Raju, P, Paul, PG, Ramsathish, S & Vijaya, L 2007, 'Population norms for frequency doubling perimetry with uncorrected refractive error', Optometry and Vision Science, vol. 84, no. 6, pp. 496-504. https://doi.org/10.1097/OPX.0b013e31806db55e

Population norms for frequency doubling perimetry with uncorrected refractive error. / Ve Ramesh, Sathyamangalam; George, Ronnie; Soni, Premal M.; Palaniappan, Lakshmanan; Raju, Prema; Paul, Pradeep G.; Ramsathish, Sivarathinasami; Vijaya, Lingam.

In: Optometry and Vision Science, Vol. 84, No. 6, 01.06.2007, p. 496-504.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Population norms for frequency doubling perimetry with uncorrected refractive error

AU - Ve Ramesh, Sathyamangalam

AU - George, Ronnie

AU - Soni, Premal M.

AU - Palaniappan, Lakshmanan

AU - Raju, Prema

AU - Paul, Pradeep G.

AU - Ramsathish, Sivarathinasami

AU - Vijaya, Lingam

PY - 2007/6/1

Y1 - 2007/6/1

N2 - PURPOSE. To compare the effect of uncorrected refractive error on threshold estimation using frequency doubling perimetry (FDP) full-threshold N-30 with emmetropia among normal subjects. METHODS. One thousand two hundred ninety-nine subjects were enrolled from the Chennai Glaucoma Study, a population-based glaucoma prevalence study. Subjects underwent a comprehensive eye examination including the FDP full-threshold N-30 test. Normal subjects (with spherical equivalent refractive errors within ±7 D) with no other ocular pathology were stratified into six groups based on the degree of myopia and hyperopia and compared with age-matched emmetropic controls. A subset of 22 subjects with higher refractive errors was assessed for within-subject effect on FDP parameters. The following FDP parameters were compared: mean deviation, pattern standard deviation, central threshold (CT), mean sensitivity (MS), paracentral points (PA), and peripheral threshold. RESULTS. The one-way analysis of variance between all refractive error groups and emmetropes showed no statistically significant difference for the mean deviation (p = 0.1002) and pattern standard deviation (p = 0.4789). FDP parameters did not show a statistically significant difference for between and within-group comparisons. The variability of FDP sensitivity (derived from the 95% confidence interval range) as a proportion of the threshold range of the instrument was 31, 41, 46, and 41% for CT, MS, PA, and peripheral sensitivity, respectively, without spectacle correction and 29, 34, 36, and 35% for CT, MS, PA, and peripheral sensitivity, respectively, with correction. The mean CT, PA, and peripheral sensitivity show a decreasing trend from central to periphery in all the refractive error groups and a similar trend was noted in the emmetropic controls. CONCLUSION. Between-subject (uncorrected ammetropes and age-matched emmetropes) and within-subject comparisons showed no statistically significant differences in any of the FDP parameters or in the contrast sensitivity estimates between the central and peripheral test locations. This finding is likely due to the high within-subject variability of FDP.

AB - PURPOSE. To compare the effect of uncorrected refractive error on threshold estimation using frequency doubling perimetry (FDP) full-threshold N-30 with emmetropia among normal subjects. METHODS. One thousand two hundred ninety-nine subjects were enrolled from the Chennai Glaucoma Study, a population-based glaucoma prevalence study. Subjects underwent a comprehensive eye examination including the FDP full-threshold N-30 test. Normal subjects (with spherical equivalent refractive errors within ±7 D) with no other ocular pathology were stratified into six groups based on the degree of myopia and hyperopia and compared with age-matched emmetropic controls. A subset of 22 subjects with higher refractive errors was assessed for within-subject effect on FDP parameters. The following FDP parameters were compared: mean deviation, pattern standard deviation, central threshold (CT), mean sensitivity (MS), paracentral points (PA), and peripheral threshold. RESULTS. The one-way analysis of variance between all refractive error groups and emmetropes showed no statistically significant difference for the mean deviation (p = 0.1002) and pattern standard deviation (p = 0.4789). FDP parameters did not show a statistically significant difference for between and within-group comparisons. The variability of FDP sensitivity (derived from the 95% confidence interval range) as a proportion of the threshold range of the instrument was 31, 41, 46, and 41% for CT, MS, PA, and peripheral sensitivity, respectively, without spectacle correction and 29, 34, 36, and 35% for CT, MS, PA, and peripheral sensitivity, respectively, with correction. The mean CT, PA, and peripheral sensitivity show a decreasing trend from central to periphery in all the refractive error groups and a similar trend was noted in the emmetropic controls. CONCLUSION. Between-subject (uncorrected ammetropes and age-matched emmetropes) and within-subject comparisons showed no statistically significant differences in any of the FDP parameters or in the contrast sensitivity estimates between the central and peripheral test locations. This finding is likely due to the high within-subject variability of FDP.

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