TY - JOUR
T1 - Potent in vitro cytotoxic and antioxidant activity of Careya arborea bark extracts
AU - Senthilkumar, Natesan
AU - Badami, Shrishailappa
AU - Cherian, Manju Mary
AU - Hariharapura, Raghu Chandrasekar
PY - 2007/5/1
Y1 - 2007/5/1
N2 - Careya arborea is used in traditional medicine for the treatment of tumors and other ailments. The successive chloroform and ethyl acetate extracts and crude 50% methanol extract exhibited potent cytotoxicity against cancerous RD, HEp-2 and HeLa cell lines. They were found to be safe against the normal Vero cell line. The methanol and aqueous extracts possessed strong antioxidant activity against many oxidants in the in vitro antioxidant screening. The total phenol content of these extracts was found to be high. The results suggest strong cytotoxic and antioxidant properties and support the ethnomedical claims for the plant.
AB - Careya arborea is used in traditional medicine for the treatment of tumors and other ailments. The successive chloroform and ethyl acetate extracts and crude 50% methanol extract exhibited potent cytotoxicity against cancerous RD, HEp-2 and HeLa cell lines. They were found to be safe against the normal Vero cell line. The methanol and aqueous extracts possessed strong antioxidant activity against many oxidants in the in vitro antioxidant screening. The total phenol content of these extracts was found to be high. The results suggest strong cytotoxic and antioxidant properties and support the ethnomedical claims for the plant.
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U2 - 10.1002/ptr.2118
DO - 10.1002/ptr.2118
M3 - Article
C2 - 17357173
AN - SCOPUS:34248179200
SN - 0951-418X
VL - 21
SP - 492
EP - 495
JO - Phytotherapy Research
JF - Phytotherapy Research
IS - 5
ER -
