Premature rupture of membrane at term

Early induction versus expectant management

Krupa Shah, Haresh Doshi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Introduction Premature rupture of membrane is managed either expectantly or actively. The purpose of the study was to assess the effectiveness of early labor induction with cervical prostaglandin E2 versus expectant management in women with term premature rupture of membrane. Material and Methods Singleton pregnancy cases with cephalic presentation reported between 37 and 41 weeks of pregnancy with PROM of \6 h and cervical dilatation \3 cm were studied over a period of 2 years. Out of 100 patients studied, half of them were managed by expectant protocol and the other half by early induction within 6 h of PROM with intracervical gel. Main outcomes measured were PROM-delivery interval, mode of delivery, neonatal and maternal morbidity, and period of maternal and/or neonatal hospitalization. Chi-square test was used to compare frequencies between two groups. Differences between means of other measurement were compared by independent t test. Results PROM-delivery interval was 22 h in expectant group, while in early induction group, it was 13 h (p value\0.001). Rate of cesarean section remained almost same in both groups. Increases in maternal-neonatal infection rate and hospital stay were noted in expectant group; however, this was not statistically significant. Conclusion Immediate labor induction with prostaglandin in cases of term PROM shortens delivery interval and maternal hospital stay with reduction in maternal-neonatal sepsis.

Original languageEnglish
Pages (from-to)172-175
Number of pages4
JournalJournal of Obstetrics and Gynecology of India
Volume62
Issue number2
DOIs
Publication statusPublished - 01-04-2012

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Rupture
Mothers
Membranes
Induced Labor
Length of Stay
Premature Rupture Fetal Membranes
First Labor Stage
Chi-Square Distribution
Dinoprostone
Cesarean Section
Prostaglandins
Hospitalization
Gels
Head
Morbidity
Pregnancy
Infection

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

Cite this

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abstract = "Introduction Premature rupture of membrane is managed either expectantly or actively. The purpose of the study was to assess the effectiveness of early labor induction with cervical prostaglandin E2 versus expectant management in women with term premature rupture of membrane. Material and Methods Singleton pregnancy cases with cephalic presentation reported between 37 and 41 weeks of pregnancy with PROM of \6 h and cervical dilatation \3 cm were studied over a period of 2 years. Out of 100 patients studied, half of them were managed by expectant protocol and the other half by early induction within 6 h of PROM with intracervical gel. Main outcomes measured were PROM-delivery interval, mode of delivery, neonatal and maternal morbidity, and period of maternal and/or neonatal hospitalization. Chi-square test was used to compare frequencies between two groups. Differences between means of other measurement were compared by independent t test. Results PROM-delivery interval was 22 h in expectant group, while in early induction group, it was 13 h (p value\0.001). Rate of cesarean section remained almost same in both groups. Increases in maternal-neonatal infection rate and hospital stay were noted in expectant group; however, this was not statistically significant. Conclusion Immediate labor induction with prostaglandin in cases of term PROM shortens delivery interval and maternal hospital stay with reduction in maternal-neonatal sepsis.",
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Premature rupture of membrane at term : Early induction versus expectant management. / Shah, Krupa; Doshi, Haresh.

In: Journal of Obstetrics and Gynecology of India, Vol. 62, No. 2, 01.04.2012, p. 172-175.

Research output: Contribution to journalArticle

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T2 - Early induction versus expectant management

AU - Shah, Krupa

AU - Doshi, Haresh

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N2 - Introduction Premature rupture of membrane is managed either expectantly or actively. The purpose of the study was to assess the effectiveness of early labor induction with cervical prostaglandin E2 versus expectant management in women with term premature rupture of membrane. Material and Methods Singleton pregnancy cases with cephalic presentation reported between 37 and 41 weeks of pregnancy with PROM of \6 h and cervical dilatation \3 cm were studied over a period of 2 years. Out of 100 patients studied, half of them were managed by expectant protocol and the other half by early induction within 6 h of PROM with intracervical gel. Main outcomes measured were PROM-delivery interval, mode of delivery, neonatal and maternal morbidity, and period of maternal and/or neonatal hospitalization. Chi-square test was used to compare frequencies between two groups. Differences between means of other measurement were compared by independent t test. Results PROM-delivery interval was 22 h in expectant group, while in early induction group, it was 13 h (p value\0.001). Rate of cesarean section remained almost same in both groups. Increases in maternal-neonatal infection rate and hospital stay were noted in expectant group; however, this was not statistically significant. Conclusion Immediate labor induction with prostaglandin in cases of term PROM shortens delivery interval and maternal hospital stay with reduction in maternal-neonatal sepsis.

AB - Introduction Premature rupture of membrane is managed either expectantly or actively. The purpose of the study was to assess the effectiveness of early labor induction with cervical prostaglandin E2 versus expectant management in women with term premature rupture of membrane. Material and Methods Singleton pregnancy cases with cephalic presentation reported between 37 and 41 weeks of pregnancy with PROM of \6 h and cervical dilatation \3 cm were studied over a period of 2 years. Out of 100 patients studied, half of them were managed by expectant protocol and the other half by early induction within 6 h of PROM with intracervical gel. Main outcomes measured were PROM-delivery interval, mode of delivery, neonatal and maternal morbidity, and period of maternal and/or neonatal hospitalization. Chi-square test was used to compare frequencies between two groups. Differences between means of other measurement were compared by independent t test. Results PROM-delivery interval was 22 h in expectant group, while in early induction group, it was 13 h (p value\0.001). Rate of cesarean section remained almost same in both groups. Increases in maternal-neonatal infection rate and hospital stay were noted in expectant group; however, this was not statistically significant. Conclusion Immediate labor induction with prostaglandin in cases of term PROM shortens delivery interval and maternal hospital stay with reduction in maternal-neonatal sepsis.

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