Preoperative Staging of Differentiated Thyroid Carcinomas: Comparison of USG and CT with Intraoperative Findings and Histopathology

Thasneem Jainulabdeen, Balakrishnan Ramaswamy, K. Devaraja, Samir M. Paruthikunnan, Ajay M. Bhandarkar

Research output: Contribution to journalArticle

Abstract

To study the efficacy of USG and CECT in preoperative staging of differentiated thyroid carcinomas in comparison to the intraoperative and histopathological findings. A prospective, observational study was conducted in a tertiary care hospital over a period of one and a half years where USG and CECT of 23 subjects with histopathologically proven differentiated thyroid malignancy were analysed to study the characteristics of the primary tumour, lymphatic metastasis and evaluate the sensitivity and specificity of the radiological investigations in comparison to the intra-operative and histopathological findings. When compared with intraoperative and histopathological T-staging, USG had an accuracy of 69.5% and 73.9% and CECT had an accuracy of 78.2% and 73.9% respectively. The sensitivity and specificity of USG and CECT in determining a malignant nodule was 71.4% and 33.3% and 52.4% and 66.7% respectively. The N-staging according to the histopathological examination findings was in agreement with that of USG in 65.2% and CECT in 65.2% patients. The sensitivity and specificity of USG was 94.4% and 41.7% and that of CECT was 92.2% and 44.4% respectively in detecting lymphatic metastasis. The sensitivity and specificity of USG was 94.4% and 44.4% and that of CECT was 92.2% and 27.3% respectively in detecting lateral compartment lymphatic metastasis. USG identifies the characteristics of the malignant nodules better and CECT has a higher identifying central compartment lymphatic metastasis. CECT should be used as an adjunct to ultrasound to determine the extent of lymphatic metastasis and staging of disease.

Original languageEnglish
Pages (from-to)327-333
Number of pages7
JournalIndian Journal of Otolaryngology and Head and Neck Surgery
Volume71
Issue number3
DOIs
Publication statusPublished - 01-09-2019

Fingerprint

Lymphatic Metastasis
Thyroid Neoplasms
Sensitivity and Specificity
Tertiary Healthcare
Tertiary Care Centers
Observational Studies
Neoplasms
Thyroid Gland
Prospective Studies

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

Cite this

@article{1f8805c05b88443b9e691fc2ec305020,
title = "Preoperative Staging of Differentiated Thyroid Carcinomas: Comparison of USG and CT with Intraoperative Findings and Histopathology",
abstract = "To study the efficacy of USG and CECT in preoperative staging of differentiated thyroid carcinomas in comparison to the intraoperative and histopathological findings. A prospective, observational study was conducted in a tertiary care hospital over a period of one and a half years where USG and CECT of 23 subjects with histopathologically proven differentiated thyroid malignancy were analysed to study the characteristics of the primary tumour, lymphatic metastasis and evaluate the sensitivity and specificity of the radiological investigations in comparison to the intra-operative and histopathological findings. When compared with intraoperative and histopathological T-staging, USG had an accuracy of 69.5{\%} and 73.9{\%} and CECT had an accuracy of 78.2{\%} and 73.9{\%} respectively. The sensitivity and specificity of USG and CECT in determining a malignant nodule was 71.4{\%} and 33.3{\%} and 52.4{\%} and 66.7{\%} respectively. The N-staging according to the histopathological examination findings was in agreement with that of USG in 65.2{\%} and CECT in 65.2{\%} patients. The sensitivity and specificity of USG was 94.4{\%} and 41.7{\%} and that of CECT was 92.2{\%} and 44.4{\%} respectively in detecting lymphatic metastasis. The sensitivity and specificity of USG was 94.4{\%} and 44.4{\%} and that of CECT was 92.2{\%} and 27.3{\%} respectively in detecting lateral compartment lymphatic metastasis. USG identifies the characteristics of the malignant nodules better and CECT has a higher identifying central compartment lymphatic metastasis. CECT should be used as an adjunct to ultrasound to determine the extent of lymphatic metastasis and staging of disease.",
author = "Thasneem Jainulabdeen and Balakrishnan Ramaswamy and K. Devaraja and Paruthikunnan, {Samir M.} and Bhandarkar, {Ajay M.}",
year = "2019",
month = "9",
day = "1",
doi = "10.1007/s12070-019-01663-5",
language = "English",
volume = "71",
pages = "327--333",
journal = "Indian Journal of Otolaryngology and Head and Neck Surgery",
issn = "2231-3796",
publisher = "Springer India",
number = "3",

}

Preoperative Staging of Differentiated Thyroid Carcinomas : Comparison of USG and CT with Intraoperative Findings and Histopathology. / Jainulabdeen, Thasneem; Ramaswamy, Balakrishnan; Devaraja, K.; Paruthikunnan, Samir M.; Bhandarkar, Ajay M.

In: Indian Journal of Otolaryngology and Head and Neck Surgery, Vol. 71, No. 3, 01.09.2019, p. 327-333.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Preoperative Staging of Differentiated Thyroid Carcinomas

T2 - Comparison of USG and CT with Intraoperative Findings and Histopathology

AU - Jainulabdeen, Thasneem

AU - Ramaswamy, Balakrishnan

AU - Devaraja, K.

AU - Paruthikunnan, Samir M.

AU - Bhandarkar, Ajay M.

PY - 2019/9/1

Y1 - 2019/9/1

N2 - To study the efficacy of USG and CECT in preoperative staging of differentiated thyroid carcinomas in comparison to the intraoperative and histopathological findings. A prospective, observational study was conducted in a tertiary care hospital over a period of one and a half years where USG and CECT of 23 subjects with histopathologically proven differentiated thyroid malignancy were analysed to study the characteristics of the primary tumour, lymphatic metastasis and evaluate the sensitivity and specificity of the radiological investigations in comparison to the intra-operative and histopathological findings. When compared with intraoperative and histopathological T-staging, USG had an accuracy of 69.5% and 73.9% and CECT had an accuracy of 78.2% and 73.9% respectively. The sensitivity and specificity of USG and CECT in determining a malignant nodule was 71.4% and 33.3% and 52.4% and 66.7% respectively. The N-staging according to the histopathological examination findings was in agreement with that of USG in 65.2% and CECT in 65.2% patients. The sensitivity and specificity of USG was 94.4% and 41.7% and that of CECT was 92.2% and 44.4% respectively in detecting lymphatic metastasis. The sensitivity and specificity of USG was 94.4% and 44.4% and that of CECT was 92.2% and 27.3% respectively in detecting lateral compartment lymphatic metastasis. USG identifies the characteristics of the malignant nodules better and CECT has a higher identifying central compartment lymphatic metastasis. CECT should be used as an adjunct to ultrasound to determine the extent of lymphatic metastasis and staging of disease.

AB - To study the efficacy of USG and CECT in preoperative staging of differentiated thyroid carcinomas in comparison to the intraoperative and histopathological findings. A prospective, observational study was conducted in a tertiary care hospital over a period of one and a half years where USG and CECT of 23 subjects with histopathologically proven differentiated thyroid malignancy were analysed to study the characteristics of the primary tumour, lymphatic metastasis and evaluate the sensitivity and specificity of the radiological investigations in comparison to the intra-operative and histopathological findings. When compared with intraoperative and histopathological T-staging, USG had an accuracy of 69.5% and 73.9% and CECT had an accuracy of 78.2% and 73.9% respectively. The sensitivity and specificity of USG and CECT in determining a malignant nodule was 71.4% and 33.3% and 52.4% and 66.7% respectively. The N-staging according to the histopathological examination findings was in agreement with that of USG in 65.2% and CECT in 65.2% patients. The sensitivity and specificity of USG was 94.4% and 41.7% and that of CECT was 92.2% and 44.4% respectively in detecting lymphatic metastasis. The sensitivity and specificity of USG was 94.4% and 44.4% and that of CECT was 92.2% and 27.3% respectively in detecting lateral compartment lymphatic metastasis. USG identifies the characteristics of the malignant nodules better and CECT has a higher identifying central compartment lymphatic metastasis. CECT should be used as an adjunct to ultrasound to determine the extent of lymphatic metastasis and staging of disease.

UR - http://www.scopus.com/inward/record.url?scp=85064749246&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85064749246&partnerID=8YFLogxK

U2 - 10.1007/s12070-019-01663-5

DO - 10.1007/s12070-019-01663-5

M3 - Article

AN - SCOPUS:85064749246

VL - 71

SP - 327

EP - 333

JO - Indian Journal of Otolaryngology and Head and Neck Surgery

JF - Indian Journal of Otolaryngology and Head and Neck Surgery

SN - 2231-3796

IS - 3

ER -