Preparation and characterization of biodegradable scaffolds of poly(lactide-co-glycolide) 50

50 and hydroxyapatite for dental applications

Kishore Ginjupalli, Ranjith Kumar Averineni, Bhat K. Mahalinga, N. Udupa

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In the present study, biodegradable scaffolds of poly(lactide-co-glycolide) PLGA 50:50 with acidic microclimate controlling additives were prepared and characterized for their degradation behavior, physical, and mechanical properties. Results indicate that scaffolds with acidic microclimate controlling additives undergo degradation without large variation in pH of the surrounding medium. Results also indicated that microclimate controlling additives did not significantly alter the physical and mechanical properties of the scaffolds. From the results, it can be concluded that PLGA 50:50 scaffolds with acidic microclimate controlling additives can be used as root replicas after the tooth extraction.

Original languageEnglish
Pages (from-to)31-44
Number of pages14
JournalComposite Interfaces
Volume21
Issue number1
DOIs
Publication statusPublished - 02-01-2014

Fingerprint

Polyglactin 910
Durapatite
Hydroxyapatite
Scaffolds
preparation
Physical properties
physical properties
mechanical properties
degradation
Degradation
Mechanical properties
teeth
replicas
polylactic acid-polyglycolic acid copolymer

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Physics and Astronomy(all)
  • Surfaces, Coatings and Films

Cite this

@article{c938719597094274a4484784f162c3b3,
title = "Preparation and characterization of biodegradable scaffolds of poly(lactide-co-glycolide) 50: 50 and hydroxyapatite for dental applications",
abstract = "In the present study, biodegradable scaffolds of poly(lactide-co-glycolide) PLGA 50:50 with acidic microclimate controlling additives were prepared and characterized for their degradation behavior, physical, and mechanical properties. Results indicate that scaffolds with acidic microclimate controlling additives undergo degradation without large variation in pH of the surrounding medium. Results also indicated that microclimate controlling additives did not significantly alter the physical and mechanical properties of the scaffolds. From the results, it can be concluded that PLGA 50:50 scaffolds with acidic microclimate controlling additives can be used as root replicas after the tooth extraction.",
author = "Kishore Ginjupalli and Averineni, {Ranjith Kumar} and Mahalinga, {Bhat K.} and N. Udupa",
year = "2014",
month = "1",
day = "2",
doi = "10.1080/15685543.2013.830523",
language = "English",
volume = "21",
pages = "31--44",
journal = "Composite Interfaces",
issn = "0927-6440",
publisher = "Taylor and Francis Ltd.",
number = "1",

}

Preparation and characterization of biodegradable scaffolds of poly(lactide-co-glycolide) 50 : 50 and hydroxyapatite for dental applications. / Ginjupalli, Kishore; Averineni, Ranjith Kumar; Mahalinga, Bhat K.; Udupa, N.

In: Composite Interfaces, Vol. 21, No. 1, 02.01.2014, p. 31-44.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Preparation and characterization of biodegradable scaffolds of poly(lactide-co-glycolide) 50

T2 - 50 and hydroxyapatite for dental applications

AU - Ginjupalli, Kishore

AU - Averineni, Ranjith Kumar

AU - Mahalinga, Bhat K.

AU - Udupa, N.

PY - 2014/1/2

Y1 - 2014/1/2

N2 - In the present study, biodegradable scaffolds of poly(lactide-co-glycolide) PLGA 50:50 with acidic microclimate controlling additives were prepared and characterized for their degradation behavior, physical, and mechanical properties. Results indicate that scaffolds with acidic microclimate controlling additives undergo degradation without large variation in pH of the surrounding medium. Results also indicated that microclimate controlling additives did not significantly alter the physical and mechanical properties of the scaffolds. From the results, it can be concluded that PLGA 50:50 scaffolds with acidic microclimate controlling additives can be used as root replicas after the tooth extraction.

AB - In the present study, biodegradable scaffolds of poly(lactide-co-glycolide) PLGA 50:50 with acidic microclimate controlling additives were prepared and characterized for their degradation behavior, physical, and mechanical properties. Results indicate that scaffolds with acidic microclimate controlling additives undergo degradation without large variation in pH of the surrounding medium. Results also indicated that microclimate controlling additives did not significantly alter the physical and mechanical properties of the scaffolds. From the results, it can be concluded that PLGA 50:50 scaffolds with acidic microclimate controlling additives can be used as root replicas after the tooth extraction.

UR - http://www.scopus.com/inward/record.url?scp=84886596702&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84886596702&partnerID=8YFLogxK

U2 - 10.1080/15685543.2013.830523

DO - 10.1080/15685543.2013.830523

M3 - Article

VL - 21

SP - 31

EP - 44

JO - Composite Interfaces

JF - Composite Interfaces

SN - 0927-6440

IS - 1

ER -