Preparation and evaluation of alginate microspheres containing norfloxacin and ciprofloxacin

K. S. Aithal, N. Udupa

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Microspheres containing norfloxacin and ciprofloxacin using Sodium and calcium alginates were prepared and the possible drug-excipient chemical interaction was evaluated by various spectral methods. There was no chemical interaction between these drugs and the alginates. The dissolution and diffusion of these drugs were delayed and the stability at various accelerated stability conditions was improved on entrappment of these drugs in alginates.

Original languageEnglish
Pages (from-to)61-67
Number of pages7
JournalIndian Journal of Pharmaceutical Sciences
Volume59
Issue number2
Publication statusPublished - 03-1997

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Alginates
Norfloxacin
Ciprofloxacin
Microspheres
Excipients
Drug Interactions
Pharmaceutical Preparations
alginic acid

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

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abstract = "Microspheres containing norfloxacin and ciprofloxacin using Sodium and calcium alginates were prepared and the possible drug-excipient chemical interaction was evaluated by various spectral methods. There was no chemical interaction between these drugs and the alginates. The dissolution and diffusion of these drugs were delayed and the stability at various accelerated stability conditions was improved on entrappment of these drugs in alginates.",
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Preparation and evaluation of alginate microspheres containing norfloxacin and ciprofloxacin. / Aithal, K. S.; Udupa, N.

In: Indian Journal of Pharmaceutical Sciences, Vol. 59, No. 2, 03.1997, p. 61-67.

Research output: Contribution to journalArticle

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