Preparation and evaluation of alginate microspheres containing norfloxacin and ciprofloxacin

K. S. Aithal, N. Udupa

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Microspheres containing norfloxacin and ciprofloxacin using Sodium and calcium alginates were prepared and the possible drug-excipient chemical interaction was evaluated by various spectral methods. There was no chemical interaction between these drugs and the alginates. The dissolution and diffusion of these drugs were delayed and the stability at various accelerated stability conditions was improved on entrappment of these drugs in alginates.

Original languageEnglish
Pages (from-to)61-67
Number of pages7
JournalIndian Journal of Pharmaceutical Sciences
Volume59
Issue number2
Publication statusPublished - 03-1997

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

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