Preparation and Evaluation of Dental Implants containing Doxycycline Hydrochloride and Tinidazole in Biodegradable Carrier

R. Nagaraju, N. Udupa

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Dental implants of doxycycline hydrochloride and tinidazole were formulated using a biodegradable carrier, Poly (ε-caprolactone), for the treatment of periodontitis. The In vitro drug release patterns and stability of these devices were studied. The formulations showed an initial burst release followed by more sustained release of the drugs throughout the period of study (42 days). The stability of the drugs were shown a marked improvement by formulating them in polymer matrix.

Original languageEnglish
Pages (from-to)405-406
Number of pages2
JournalIndian Journal of Pharmaceutical Sciences
Issue number6
Publication statusPublished - 11-1998


All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

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