Prescribing pattern for osteoarthritis in A tertiary care hospital

S. D. Ullal, S. Narendranath, R. K. Kamath, Pai Mrsm, S. U. Kamath, D. Savur Amarnath

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Treatment of osteoarthritis aims at reducing pain and improving mobility. NSAIDs are widely prescribed for symptomatic relief despite well-known adverse effects. Paracetamol with its better safety profile is recommended as the initial analgesic of choice. SYSADOA is a generic term used for symptomatic slow acting drugs for osteoarthitis, and includes glucosamine sulphate and related compounds, chondroitin sulphate, and diacerein. SYSADOA when compared to NSAIDs, are safer, comparable in symptomatic efficacy and better in structure modifying efficacy in osteoarthritis. A drug utilization study is considered to be one of the most effective methods to assess and evaluate the prescribing attitude of physicians. Despite the considerable socio-economic impact of OA, not many studies have established the drug-prescribing trend in India. Hence we decided to study the prescribing pattern of SYSADOA, paracetamol and NSAIDs in OA vis-à-vis the standard recommendations and in the process provide constructive feedback to prescribing clinicians. Methods: Prescriptions for osteoarthritic patients collected cross-sectionally for six months from an orthopaedic outpatient unit in a tertiary care hospital, were analysed. Results: Out of 154 prescriptions analysed, 7% were prescribed glucosamine and chondroitin, while 4% received diacerein. Paracetamol was prescribed in 17% cases. NSAIDs were prescribed in 84%, with 27% receiving two or more NSAIDs simultaneously. Conclusion: SYSADOA and paracetamol were under-prescribed while NSAIDs were probably over-prescribed.

Original languageEnglish
Pages (from-to)2421-2426
Number of pages6
JournalJournal of Clinical and Diagnostic Research
Volume4
Issue number3
Publication statusPublished - 17-12-2010

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Non-Steroidal Anti-Inflammatory Agents
Tertiary Healthcare
Tertiary Care Centers
Osteoarthritis
diacetylrhein
Acetaminophen
Glucosamine
Prescriptions
Chondroitin
Pharmaceutical Preparations
Drug Utilization
Drug Prescriptions
Chondroitin Sulfates
Orthopedics
Analgesics
India
Outpatients
Economics
Physicians
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All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

Ullal, S. D., Narendranath, S., Kamath, R. K., Mrsm, P., Kamath, S. U., & Savur Amarnath, D. (2010). Prescribing pattern for osteoarthritis in A tertiary care hospital. Journal of Clinical and Diagnostic Research, 4(3), 2421-2426.
Ullal, S. D. ; Narendranath, S. ; Kamath, R. K. ; Mrsm, Pai ; Kamath, S. U. ; Savur Amarnath, D. / Prescribing pattern for osteoarthritis in A tertiary care hospital. In: Journal of Clinical and Diagnostic Research. 2010 ; Vol. 4, No. 3. pp. 2421-2426.
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Ullal, SD, Narendranath, S, Kamath, RK, Mrsm, P, Kamath, SU & Savur Amarnath, D 2010, 'Prescribing pattern for osteoarthritis in A tertiary care hospital', Journal of Clinical and Diagnostic Research, vol. 4, no. 3, pp. 2421-2426.

Prescribing pattern for osteoarthritis in A tertiary care hospital. / Ullal, S. D.; Narendranath, S.; Kamath, R. K.; Mrsm, Pai; Kamath, S. U.; Savur Amarnath, D.

In: Journal of Clinical and Diagnostic Research, Vol. 4, No. 3, 17.12.2010, p. 2421-2426.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Prescribing pattern for osteoarthritis in A tertiary care hospital

AU - Ullal, S. D.

AU - Narendranath, S.

AU - Kamath, R. K.

AU - Mrsm, Pai

AU - Kamath, S. U.

AU - Savur Amarnath, D.

PY - 2010/12/17

Y1 - 2010/12/17

N2 - Background: Treatment of osteoarthritis aims at reducing pain and improving mobility. NSAIDs are widely prescribed for symptomatic relief despite well-known adverse effects. Paracetamol with its better safety profile is recommended as the initial analgesic of choice. SYSADOA is a generic term used for symptomatic slow acting drugs for osteoarthitis, and includes glucosamine sulphate and related compounds, chondroitin sulphate, and diacerein. SYSADOA when compared to NSAIDs, are safer, comparable in symptomatic efficacy and better in structure modifying efficacy in osteoarthritis. A drug utilization study is considered to be one of the most effective methods to assess and evaluate the prescribing attitude of physicians. Despite the considerable socio-economic impact of OA, not many studies have established the drug-prescribing trend in India. Hence we decided to study the prescribing pattern of SYSADOA, paracetamol and NSAIDs in OA vis-à-vis the standard recommendations and in the process provide constructive feedback to prescribing clinicians. Methods: Prescriptions for osteoarthritic patients collected cross-sectionally for six months from an orthopaedic outpatient unit in a tertiary care hospital, were analysed. Results: Out of 154 prescriptions analysed, 7% were prescribed glucosamine and chondroitin, while 4% received diacerein. Paracetamol was prescribed in 17% cases. NSAIDs were prescribed in 84%, with 27% receiving two or more NSAIDs simultaneously. Conclusion: SYSADOA and paracetamol were under-prescribed while NSAIDs were probably over-prescribed.

AB - Background: Treatment of osteoarthritis aims at reducing pain and improving mobility. NSAIDs are widely prescribed for symptomatic relief despite well-known adverse effects. Paracetamol with its better safety profile is recommended as the initial analgesic of choice. SYSADOA is a generic term used for symptomatic slow acting drugs for osteoarthitis, and includes glucosamine sulphate and related compounds, chondroitin sulphate, and diacerein. SYSADOA when compared to NSAIDs, are safer, comparable in symptomatic efficacy and better in structure modifying efficacy in osteoarthritis. A drug utilization study is considered to be one of the most effective methods to assess and evaluate the prescribing attitude of physicians. Despite the considerable socio-economic impact of OA, not many studies have established the drug-prescribing trend in India. Hence we decided to study the prescribing pattern of SYSADOA, paracetamol and NSAIDs in OA vis-à-vis the standard recommendations and in the process provide constructive feedback to prescribing clinicians. Methods: Prescriptions for osteoarthritic patients collected cross-sectionally for six months from an orthopaedic outpatient unit in a tertiary care hospital, were analysed. Results: Out of 154 prescriptions analysed, 7% were prescribed glucosamine and chondroitin, while 4% received diacerein. Paracetamol was prescribed in 17% cases. NSAIDs were prescribed in 84%, with 27% receiving two or more NSAIDs simultaneously. Conclusion: SYSADOA and paracetamol were under-prescribed while NSAIDs were probably over-prescribed.

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JO - Journal of Clinical and Diagnostic Research

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Ullal SD, Narendranath S, Kamath RK, Mrsm P, Kamath SU, Savur Amarnath D. Prescribing pattern for osteoarthritis in A tertiary care hospital. Journal of Clinical and Diagnostic Research. 2010 Dec 17;4(3):2421-2426.