Prevalence and predictors of renal artery stenosis in patients undergoing peripheral and coronary angiography

Anand N. Shukla, Tarun H. Madan, Ashwal A. Jayaram, Vivek B. Kute, Jayesh R. Rawal, A. P. Manjunath, Satyam Udhreja

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Renal artery stenosis is a potential cause of secondary hypertension, ischemic nephropathy and end-stage renal disease. Atherosclerosis is by far the most common etiology of renal artery stenosis in elderly. We investigated whether the presence of significant atherosclerotic renal artery stenosis (ARAS) with luminal diameter narrowing ≥50 % could be predicted in patients undergoing peripheral and coronary angiography. Methods: The records of 3,500 consecutive patients undergoing simultaneous renal angiography along with peripheral and coronary angiography were reviewed. The patients with known renal artery disease were excluded. Results: Prevalence of ARAS was 5.7 %. Significant ARAS (luminal diameter narrowing ≥50 %) was present in 139 patients (3.9 %). Hypertension with altered serum creatinine and triple-vessel CAD were associated with significant renal artery stenosis in multivariate analysis. No significant relationship between the involved coronary arteries like left anterior descending, left circumflex, right coronary artery and ARAS was found. Only hypertension and altered serum creatinine were associated with bilateral ARAS. Extent of CAD or risk factors like diabetes, hyperlipidemia or smoking did not predict the unilateral or bilateral ARAS. Conclusion: Prevalence of ARAS among the patients in routine cardiac catheterization was 5.7 %. Hypertension is closely associated with significant ARAS. Significant CAD in the form of triple-vessel disease and altered renal function tests are closely associated with ARAS. They predict the presence of significant renal artery stenosis in patients undergoing routine peripheral and coronary angiography. Moreover, hypertension and altered renal functions predict bilateral ARAS.

Original languageEnglish
Pages (from-to)1629-1635
Number of pages7
JournalInternational Urology and Nephrology
Volume45
Issue number6
DOIs
Publication statusPublished - 01-12-2013

Fingerprint

Renal Artery Obstruction
Coronary Angiography
Hypertension
Creatinine
Coronary Vessels
Kidney
Renal Hypertension
Renal Artery
Cardiac Catheterization
Hyperlipidemias
Serum
Chronic Kidney Failure

All Science Journal Classification (ASJC) codes

  • Nephrology
  • Urology

Cite this

Shukla, Anand N. ; Madan, Tarun H. ; Jayaram, Ashwal A. ; Kute, Vivek B. ; Rawal, Jayesh R. ; Manjunath, A. P. ; Udhreja, Satyam. / Prevalence and predictors of renal artery stenosis in patients undergoing peripheral and coronary angiography. In: International Urology and Nephrology. 2013 ; Vol. 45, No. 6. pp. 1629-1635.
@article{7558d65e08574f13be8e99f26b2d4f8f,
title = "Prevalence and predictors of renal artery stenosis in patients undergoing peripheral and coronary angiography",
abstract = "Background: Renal artery stenosis is a potential cause of secondary hypertension, ischemic nephropathy and end-stage renal disease. Atherosclerosis is by far the most common etiology of renal artery stenosis in elderly. We investigated whether the presence of significant atherosclerotic renal artery stenosis (ARAS) with luminal diameter narrowing ≥50 {\%} could be predicted in patients undergoing peripheral and coronary angiography. Methods: The records of 3,500 consecutive patients undergoing simultaneous renal angiography along with peripheral and coronary angiography were reviewed. The patients with known renal artery disease were excluded. Results: Prevalence of ARAS was 5.7 {\%}. Significant ARAS (luminal diameter narrowing ≥50 {\%}) was present in 139 patients (3.9 {\%}). Hypertension with altered serum creatinine and triple-vessel CAD were associated with significant renal artery stenosis in multivariate analysis. No significant relationship between the involved coronary arteries like left anterior descending, left circumflex, right coronary artery and ARAS was found. Only hypertension and altered serum creatinine were associated with bilateral ARAS. Extent of CAD or risk factors like diabetes, hyperlipidemia or smoking did not predict the unilateral or bilateral ARAS. Conclusion: Prevalence of ARAS among the patients in routine cardiac catheterization was 5.7 {\%}. Hypertension is closely associated with significant ARAS. Significant CAD in the form of triple-vessel disease and altered renal function tests are closely associated with ARAS. They predict the presence of significant renal artery stenosis in patients undergoing routine peripheral and coronary angiography. Moreover, hypertension and altered renal functions predict bilateral ARAS.",
author = "Shukla, {Anand N.} and Madan, {Tarun H.} and Jayaram, {Ashwal A.} and Kute, {Vivek B.} and Rawal, {Jayesh R.} and Manjunath, {A. P.} and Satyam Udhreja",
year = "2013",
month = "12",
day = "1",
doi = "10.1007/s11255-013-0435-x",
language = "English",
volume = "45",
pages = "1629--1635",
journal = "International Urology and Nephrology",
issn = "0301-1623",
publisher = "Springer Netherlands",
number = "6",

}

Prevalence and predictors of renal artery stenosis in patients undergoing peripheral and coronary angiography. / Shukla, Anand N.; Madan, Tarun H.; Jayaram, Ashwal A.; Kute, Vivek B.; Rawal, Jayesh R.; Manjunath, A. P.; Udhreja, Satyam.

In: International Urology and Nephrology, Vol. 45, No. 6, 01.12.2013, p. 1629-1635.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Prevalence and predictors of renal artery stenosis in patients undergoing peripheral and coronary angiography

AU - Shukla, Anand N.

AU - Madan, Tarun H.

AU - Jayaram, Ashwal A.

AU - Kute, Vivek B.

AU - Rawal, Jayesh R.

AU - Manjunath, A. P.

AU - Udhreja, Satyam

PY - 2013/12/1

Y1 - 2013/12/1

N2 - Background: Renal artery stenosis is a potential cause of secondary hypertension, ischemic nephropathy and end-stage renal disease. Atherosclerosis is by far the most common etiology of renal artery stenosis in elderly. We investigated whether the presence of significant atherosclerotic renal artery stenosis (ARAS) with luminal diameter narrowing ≥50 % could be predicted in patients undergoing peripheral and coronary angiography. Methods: The records of 3,500 consecutive patients undergoing simultaneous renal angiography along with peripheral and coronary angiography were reviewed. The patients with known renal artery disease were excluded. Results: Prevalence of ARAS was 5.7 %. Significant ARAS (luminal diameter narrowing ≥50 %) was present in 139 patients (3.9 %). Hypertension with altered serum creatinine and triple-vessel CAD were associated with significant renal artery stenosis in multivariate analysis. No significant relationship between the involved coronary arteries like left anterior descending, left circumflex, right coronary artery and ARAS was found. Only hypertension and altered serum creatinine were associated with bilateral ARAS. Extent of CAD or risk factors like diabetes, hyperlipidemia or smoking did not predict the unilateral or bilateral ARAS. Conclusion: Prevalence of ARAS among the patients in routine cardiac catheterization was 5.7 %. Hypertension is closely associated with significant ARAS. Significant CAD in the form of triple-vessel disease and altered renal function tests are closely associated with ARAS. They predict the presence of significant renal artery stenosis in patients undergoing routine peripheral and coronary angiography. Moreover, hypertension and altered renal functions predict bilateral ARAS.

AB - Background: Renal artery stenosis is a potential cause of secondary hypertension, ischemic nephropathy and end-stage renal disease. Atherosclerosis is by far the most common etiology of renal artery stenosis in elderly. We investigated whether the presence of significant atherosclerotic renal artery stenosis (ARAS) with luminal diameter narrowing ≥50 % could be predicted in patients undergoing peripheral and coronary angiography. Methods: The records of 3,500 consecutive patients undergoing simultaneous renal angiography along with peripheral and coronary angiography were reviewed. The patients with known renal artery disease were excluded. Results: Prevalence of ARAS was 5.7 %. Significant ARAS (luminal diameter narrowing ≥50 %) was present in 139 patients (3.9 %). Hypertension with altered serum creatinine and triple-vessel CAD were associated with significant renal artery stenosis in multivariate analysis. No significant relationship between the involved coronary arteries like left anterior descending, left circumflex, right coronary artery and ARAS was found. Only hypertension and altered serum creatinine were associated with bilateral ARAS. Extent of CAD or risk factors like diabetes, hyperlipidemia or smoking did not predict the unilateral or bilateral ARAS. Conclusion: Prevalence of ARAS among the patients in routine cardiac catheterization was 5.7 %. Hypertension is closely associated with significant ARAS. Significant CAD in the form of triple-vessel disease and altered renal function tests are closely associated with ARAS. They predict the presence of significant renal artery stenosis in patients undergoing routine peripheral and coronary angiography. Moreover, hypertension and altered renal functions predict bilateral ARAS.

UR - http://www.scopus.com/inward/record.url?scp=84890791281&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84890791281&partnerID=8YFLogxK

U2 - 10.1007/s11255-013-0435-x

DO - 10.1007/s11255-013-0435-x

M3 - Article

VL - 45

SP - 1629

EP - 1635

JO - International Urology and Nephrology

JF - International Urology and Nephrology

SN - 0301-1623

IS - 6

ER -