Prevalence of gingival overgrowth among elderly patients under amlodipine therapy at a large Indian teaching hospital

Rohit Karnik, K. Mahalinga Bhat, G. Subraya Bhat

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objectives: To determine the prevalence of amlodipine-induced gingival overgrowth (GO) among elderly subjects attending an Indian teaching hospital and find any association with demographic factors, drug variables, oral hygiene status and gingival inflammation. Methods: A cross-sectional pilot study included 157 dentate patients aged 60 years or more, taking Amlodipine for at least 3 months. Data were collected from past medical records and oral examination. Clinical assessment of GO was correlated with patient's age, gender, drug dosage (2.5, 5 or 10 mg/day), duration of drug therapy (3-4, 4-6, 6-12, 12-24 and >24 months) and also with subjects' plaque index and gingival index scores. Results: Eight patients (5.09%) had GO. No statistically significant relation was observed between age (p = 0.79), gender (p = 0.56), drug dosage (p = 0.25) and duration of drug intake (p = 0.62) and prevalence of GO. GO prevalence related highly significantly (p < 0.001) with plaque and gingival index scores. Conclusions: Prevalence of amlodipine-associated GO in the sample of elderly Indian patients was noted higher than that previously reported. Plaque and gingival inflammation were highly correlated with this condition, while demographic characteristics and drug dosage did not relate significantly.

Original languageEnglish
Pages (from-to)209-213
Number of pages5
JournalGerodontology
Volume29
Issue number3
DOIs
Publication statusPublished - 01-09-2012

Fingerprint

Gingival Overgrowth
Amlodipine
Teaching Hospitals
Periodontal Index
Pharmaceutical Preparations
Therapeutics
Demography
Inflammation
Oral Diagnosis
Oral Hygiene
Medical Records
Cross-Sectional Studies
Drug Therapy

All Science Journal Classification (ASJC) codes

  • Dentistry(all)
  • Geriatrics and Gerontology

Cite this

Karnik, Rohit ; Bhat, K. Mahalinga ; Subraya Bhat, G. / Prevalence of gingival overgrowth among elderly patients under amlodipine therapy at a large Indian teaching hospital. In: Gerodontology. 2012 ; Vol. 29, No. 3. pp. 209-213.
@article{26fb896d25cb4ff182f5c97a5ebbce92,
title = "Prevalence of gingival overgrowth among elderly patients under amlodipine therapy at a large Indian teaching hospital",
abstract = "Objectives: To determine the prevalence of amlodipine-induced gingival overgrowth (GO) among elderly subjects attending an Indian teaching hospital and find any association with demographic factors, drug variables, oral hygiene status and gingival inflammation. Methods: A cross-sectional pilot study included 157 dentate patients aged 60 years or more, taking Amlodipine for at least 3 months. Data were collected from past medical records and oral examination. Clinical assessment of GO was correlated with patient's age, gender, drug dosage (2.5, 5 or 10 mg/day), duration of drug therapy (3-4, 4-6, 6-12, 12-24 and >24 months) and also with subjects' plaque index and gingival index scores. Results: Eight patients (5.09{\%}) had GO. No statistically significant relation was observed between age (p = 0.79), gender (p = 0.56), drug dosage (p = 0.25) and duration of drug intake (p = 0.62) and prevalence of GO. GO prevalence related highly significantly (p < 0.001) with plaque and gingival index scores. Conclusions: Prevalence of amlodipine-associated GO in the sample of elderly Indian patients was noted higher than that previously reported. Plaque and gingival inflammation were highly correlated with this condition, while demographic characteristics and drug dosage did not relate significantly.",
author = "Rohit Karnik and Bhat, {K. Mahalinga} and {Subraya Bhat}, G.",
year = "2012",
month = "9",
day = "1",
doi = "10.1111/j.1741-2358.2011.00603.x",
language = "English",
volume = "29",
pages = "209--213",
journal = "Gerodontology",
issn = "0734-0664",
publisher = "Blackwell Munksgaard",
number = "3",

}

Prevalence of gingival overgrowth among elderly patients under amlodipine therapy at a large Indian teaching hospital. / Karnik, Rohit; Bhat, K. Mahalinga; Subraya Bhat, G.

In: Gerodontology, Vol. 29, No. 3, 01.09.2012, p. 209-213.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Prevalence of gingival overgrowth among elderly patients under amlodipine therapy at a large Indian teaching hospital

AU - Karnik, Rohit

AU - Bhat, K. Mahalinga

AU - Subraya Bhat, G.

PY - 2012/9/1

Y1 - 2012/9/1

N2 - Objectives: To determine the prevalence of amlodipine-induced gingival overgrowth (GO) among elderly subjects attending an Indian teaching hospital and find any association with demographic factors, drug variables, oral hygiene status and gingival inflammation. Methods: A cross-sectional pilot study included 157 dentate patients aged 60 years or more, taking Amlodipine for at least 3 months. Data were collected from past medical records and oral examination. Clinical assessment of GO was correlated with patient's age, gender, drug dosage (2.5, 5 or 10 mg/day), duration of drug therapy (3-4, 4-6, 6-12, 12-24 and >24 months) and also with subjects' plaque index and gingival index scores. Results: Eight patients (5.09%) had GO. No statistically significant relation was observed between age (p = 0.79), gender (p = 0.56), drug dosage (p = 0.25) and duration of drug intake (p = 0.62) and prevalence of GO. GO prevalence related highly significantly (p < 0.001) with plaque and gingival index scores. Conclusions: Prevalence of amlodipine-associated GO in the sample of elderly Indian patients was noted higher than that previously reported. Plaque and gingival inflammation were highly correlated with this condition, while demographic characteristics and drug dosage did not relate significantly.

AB - Objectives: To determine the prevalence of amlodipine-induced gingival overgrowth (GO) among elderly subjects attending an Indian teaching hospital and find any association with demographic factors, drug variables, oral hygiene status and gingival inflammation. Methods: A cross-sectional pilot study included 157 dentate patients aged 60 years or more, taking Amlodipine for at least 3 months. Data were collected from past medical records and oral examination. Clinical assessment of GO was correlated with patient's age, gender, drug dosage (2.5, 5 or 10 mg/day), duration of drug therapy (3-4, 4-6, 6-12, 12-24 and >24 months) and also with subjects' plaque index and gingival index scores. Results: Eight patients (5.09%) had GO. No statistically significant relation was observed between age (p = 0.79), gender (p = 0.56), drug dosage (p = 0.25) and duration of drug intake (p = 0.62) and prevalence of GO. GO prevalence related highly significantly (p < 0.001) with plaque and gingival index scores. Conclusions: Prevalence of amlodipine-associated GO in the sample of elderly Indian patients was noted higher than that previously reported. Plaque and gingival inflammation were highly correlated with this condition, while demographic characteristics and drug dosage did not relate significantly.

UR - http://www.scopus.com/inward/record.url?scp=84865211208&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84865211208&partnerID=8YFLogxK

U2 - 10.1111/j.1741-2358.2011.00603.x

DO - 10.1111/j.1741-2358.2011.00603.x

M3 - Article

C2 - 22506838

AN - SCOPUS:84865211208

VL - 29

SP - 209

EP - 213

JO - Gerodontology

JF - Gerodontology

SN - 0734-0664

IS - 3

ER -