Primary clear cell carcinoma of the nasopharynx

Deviprasad Dosemane, Flora D. Lobo, Suja S. Sreedharan

Research output: Contribution to journalArticle

Abstract

A 22-year-old female with epistaxis and nose block had a pink, smooth, mucosa covered lesion occupying the nasopharynx. The histopathology and immunohistochemistry of the lesion confirmed the diagnosis of clear cell carcinoma (CCC). Detailed evaluation ruled out a primary tumor elsewhere in the body. After complete excision of the tumor patient received radiotherapy (60 Gray in 30 fractions over 6 weeks). Patient is recurrence free on her 3-year follow-up. Primary CCC of the head and neck is rare. In the past 30 years, less than 100 cases have been reported in English literature. Out of these, only nine cases had nasopharyngeal origin. The literature review of those cases along with our case report suggest that complete excision of nasopharyngeal CCC along with radiotherapy leads to prolonged recurrence free interval. However, extensive tumors of nasopharynx exhibit poor prognosis with repeated local recurrences.

Original languageEnglish
Pages (from-to)928-930
Number of pages3
JournalJournal of Cancer Research and Therapeutics
Volume11
Issue number4
DOIs
Publication statusPublished - 01-10-2015

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Nasopharynx
Carcinoma
Recurrence
Radiotherapy
Literature
Neoplasms
Epistaxis
Nose
Mucous Membrane
Neck
Immunohistochemistry
Head

All Science Journal Classification (ASJC) codes

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

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Primary clear cell carcinoma of the nasopharynx. / Dosemane, Deviprasad; Lobo, Flora D.; Sreedharan, Suja S.

In: Journal of Cancer Research and Therapeutics, Vol. 11, No. 4, 01.10.2015, p. 928-930.

Research output: Contribution to journalArticle

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