Primary meningoencephalitis by Naegleria fowleri: first reported case from Mangalore, South India

Shalini Shenoy, Godwin Wilson, H V Prashanth, K Vidyalakshmi, B Dhanashree, R Bharath

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

A fatal case of primary amebic meningoencephalitis (PAM) in a 5-month-old infant is described. The disease may have been contracted during bathing. The source of water was from an artificial well. The clinical presentation, the isolation of the ameba from the cerebrospinal fluid, the poor response to amphotericin B, and the ultimate fatal outcome are all consistent with the diagnosis of PAM. On the basis of its ability to grow at temperatures above 30 degrees C, the morphology of the trophozoite, and the presence of flagellate forms, the ameba was identified as Naegleria fowleri. Pathogenic N. fowleri amebae were recovered from samples of water from the well. To our knowledge this case represents the second case of PAM in an infant in the absence of the history of swimming.

Original languageEnglish
Pages (from-to)309-10
Number of pages2
JournalJournal of Clinical Microbiology
Volume40
Issue number1
Publication statusPublished - 01-2002

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Naegleria fowleri
Meningoencephalitis
Amoeba
India
Water Wells
Trophozoites
Fatal Outcome
Amphotericin B
Cerebrospinal Fluid
History
Temperature
Water
Primary amebic meningoencephalitis

Cite this

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title = "Primary meningoencephalitis by Naegleria fowleri: first reported case from Mangalore, South India",
abstract = "A fatal case of primary amebic meningoencephalitis (PAM) in a 5-month-old infant is described. The disease may have been contracted during bathing. The source of water was from an artificial well. The clinical presentation, the isolation of the ameba from the cerebrospinal fluid, the poor response to amphotericin B, and the ultimate fatal outcome are all consistent with the diagnosis of PAM. On the basis of its ability to grow at temperatures above 30 degrees C, the morphology of the trophozoite, and the presence of flagellate forms, the ameba was identified as Naegleria fowleri. Pathogenic N. fowleri amebae were recovered from samples of water from the well. To our knowledge this case represents the second case of PAM in an infant in the absence of the history of swimming.",
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Primary meningoencephalitis by Naegleria fowleri : first reported case from Mangalore, South India. / Shenoy, Shalini; Wilson, Godwin; Prashanth, H V; Vidyalakshmi, K; Dhanashree, B; Bharath, R.

In: Journal of Clinical Microbiology, Vol. 40, No. 1, 01.2002, p. 309-10.

Research output: Contribution to journalArticle

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T1 - Primary meningoencephalitis by Naegleria fowleri

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AU - Shenoy, Shalini

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