Primary squamous cell carcinoma of thyroid is a very rare malignant disease because thyroid gland lacks squamous cells. The disease is almost fatal. Only around 60 cases have been reported in literature. Its incidence is less than 1 % of all thyroid malignancies. The overall survival rate is less than 1 year after the diagnosis. Here we report a rare case of a 70 year old lady who presented with sudden increase in the size of swelling associated with pain and obstructive symptoms in long standing thyroid swelling. Considering patient’s age and inoperable nature of disease we treated the patient with concurrent chemoradiation.
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