Production of High Fructose Syrup with a barium alginate entrapped new streptomycete producing glucose isomerase

K. Sambamurthy, P. Ellaiah, V. M. Subrahmanyam

Research output: Contribution to journalArticle


A new streptomycete S. sambaensis having 122 u/g of glucose isomerase activity was used in the production of High Fructose Syrup. Entrapment of the organism in calcium, strontium and barium alginate gels revealed that Ba alginate is better than the other two from conversion and economical point of view. The organism, after crosslinking with 0.6% aqueous glutaraldehyde, was entrapped in Ba alginate gel. This system gave 40% conversion upto 7 cycles in a batch process. A semi-continuously operated 2.5 cm dia packed column employing such an immobilised material produced 42% equilibrium conversion for 28.5 days with a fructose production of 265.9 g for 6.17 g of dry mycelium.

Original languageEnglish
Pages (from-to)163-166
Number of pages4
JournalIndian Drugs
Issue number3
Publication statusPublished - 01-03-1999


All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery

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