Profile of pancreatic tumors at a tertiary care center

P. Nandan, M. Nirupama, J. R. Kini, S. Gopal, K. K. Sahu, S. Rai

Research output: Contribution to journalArticle

Abstract

Background: Pancreas, a relatively inaccessible organ, poses diagnostic difficulties with overlapping presentation among benign and malignant tumors. In the present study, pancreatic aspirates obtained by computed tomography (CT) guided procedures were used for cytodiagnosis. Our study aims at correlating clinical, cytological, biochemical, and histopathological results in obtaining a final diagnosis. Methodology: A retrospective study of 2 years was done which included 32 cases of pancreatic tumors at a tertiary care center. Patient data were retrieved and analyzed. Results: Twenty-seven of the 32 (84.37%) cases were malignant tumors. Age distribution in malignant tumors was predominantly seen in the fourth to eighth decade, whereas in benign, it ranged in the second to third decade. Thirteen out of the 32 (40.62%) cases reported were females, with male:female ratio of 1.46:1. The most common presenting symptom was abdominal pain followed by jaundice and vomiting. Three of the 32 cases had visceral metastasis at the time of diagnosis. CT-guided aspirates in most cases yielded diagnostic material. Cytological and histopathological results concurred except for three cases. Cancer Antigen 19-9 was worked up for 14 of 27 malignant cases, 11 of which showed grossly elevated values (700-7000), and three cases showed mildly elevated values (100-300). Three of the four benign cases worked up for CA 19-9 showed normal values. Conclusions: Among the mass forming lesions in pancreas, malignancy was more common compared to benign tumors. A multidisciplinary approach in the assessment and diagnosis of pancreatic tumors yields accurate results in spite of the limitations faced in obtaining adequate samples by needle aspirates.

Original languageEnglish
Pages (from-to)296-299
Number of pages4
JournalIndian Journal of Cancer
Volume53
Issue number2
DOIs
Publication statusPublished - 01-04-2016

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Tertiary Care Centers
Neoplasms
Pancreas
Tomography
Cytodiagnosis
Age Distribution
Jaundice
Abdominal Pain
Needles
Vomiting
Reference Values
Retrospective Studies
Neoplasm Metastasis
Antigens

All Science Journal Classification (ASJC) codes

  • Oncology

Cite this

Nandan, P. ; Nirupama, M. ; Kini, J. R. ; Gopal, S. ; Sahu, K. K. ; Rai, S. / Profile of pancreatic tumors at a tertiary care center. In: Indian Journal of Cancer. 2016 ; Vol. 53, No. 2. pp. 296-299.
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Profile of pancreatic tumors at a tertiary care center. / Nandan, P.; Nirupama, M.; Kini, J. R.; Gopal, S.; Sahu, K. K.; Rai, S.

In: Indian Journal of Cancer, Vol. 53, No. 2, 01.04.2016, p. 296-299.

Research output: Contribution to journalArticle

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