Abstract
The leaves of Pimenta dioica (L) Merril (Fam: Myrtaceae) were used as medicine for pain, arthritis, fever and stress in the folklore medicine at Kerala and Mangalore. The berries are commonly known as Allspice in culinary natives of Kerala and Mangalore. The high total phenolic content in the berries and leaves were reported for antioxidant activity: In the present study we tried the alcoholic extract of leaves for protection in cyclophospamide induced myelosuppression in Swiss mice. The oral doses (250, 500, 750 mg/kg/day) showed statistically significant protection of myelosuppression.
| Original language | English |
|---|---|
| Pages (from-to) | 719-723 |
| Number of pages | 5 |
| Journal | Pharmacologyonline |
| Volume | 3 |
| Publication status | Published - 2008 |
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All Science Journal Classification (ASJC) codes
- Drug Discovery
- Pharmacology
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Protection of cyclophosphamide induced myelosuppression by alcoholic extract of pimenta dioica leaves in mice. / Nayak, Yogendra; Abhilash, D.
In: Pharmacologyonline, Vol. 3, 2008, p. 719-723.Research output: Contribution to journal › Article
TY - JOUR
T1 - Protection of cyclophosphamide induced myelosuppression by alcoholic extract of pimenta dioica leaves in mice
AU - Nayak, Yogendra
AU - Abhilash, D.
PY - 2008
Y1 - 2008
N2 - The leaves of Pimenta dioica (L) Merril (Fam: Myrtaceae) were used as medicine for pain, arthritis, fever and stress in the folklore medicine at Kerala and Mangalore. The berries are commonly known as Allspice in culinary natives of Kerala and Mangalore. The high total phenolic content in the berries and leaves were reported for antioxidant activity: In the present study we tried the alcoholic extract of leaves for protection in cyclophospamide induced myelosuppression in Swiss mice. The oral doses (250, 500, 750 mg/kg/day) showed statistically significant protection of myelosuppression.
AB - The leaves of Pimenta dioica (L) Merril (Fam: Myrtaceae) were used as medicine for pain, arthritis, fever and stress in the folklore medicine at Kerala and Mangalore. The berries are commonly known as Allspice in culinary natives of Kerala and Mangalore. The high total phenolic content in the berries and leaves were reported for antioxidant activity: In the present study we tried the alcoholic extract of leaves for protection in cyclophospamide induced myelosuppression in Swiss mice. The oral doses (250, 500, 750 mg/kg/day) showed statistically significant protection of myelosuppression.
UR - http://www.scopus.com/inward/record.url?scp=58149250206&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=58149250206&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:58149250206
VL - 3
SP - 719
EP - 723
JO - Pharmacologyonline
JF - Pharmacologyonline
SN - 1827-8620
ER -