Protein structure prediction on 2D square HP lattice with revised fitness function

Sandhya Parasnath Dubey, N. Gopalakrishna Kini, S. Balaji, M. Sathish Kumar

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In order to understand the structure and folding of proteins, Hydrophobic-Polar (HP) model on 2D square lattice is one of the most explored models but parity problem of square lattice make it inefficient for biological applications. This work is dedicated to solve parity issues in 2D square lattice model. This work proposes a revised energy function and presents a case study for protein structure prediction (PSP). A novel approach to evaluate the structure modeling and protein folding problem over HP model is presented in this paper. This evaluation approach may enhance the quality and effectiveness of the computational approaches developed to address the PSP at coarse level.

Original languageEnglish
Title of host publication2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1732-1736
Number of pages5
Volume2017-January
ISBN (Electronic)9781509063673
DOIs
Publication statusPublished - 30-11-2017
Event2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017 - Manipal, Mangalore, India
Duration: 13-09-201716-09-2017

Conference

Conference2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017
CountryIndia
CityManipal, Mangalore
Period13-09-1716-09-17

Fingerprint

Proteins
Protein folding

All Science Journal Classification (ASJC) codes

  • Computer Networks and Communications
  • Computer Science Applications
  • Information Systems

Cite this

Dubey, S. P., Gopalakrishna Kini, N., Balaji, S., & Sathish Kumar, M. (2017). Protein structure prediction on 2D square HP lattice with revised fitness function. In 2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017 (Vol. 2017-January, pp. 1732-1736). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICACCI.2017.8126094
Dubey, Sandhya Parasnath ; Gopalakrishna Kini, N. ; Balaji, S. ; Sathish Kumar, M. / Protein structure prediction on 2D square HP lattice with revised fitness function. 2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017. Vol. 2017-January Institute of Electrical and Electronics Engineers Inc., 2017. pp. 1732-1736
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Dubey, SP, Gopalakrishna Kini, N, Balaji, S & Sathish Kumar, M 2017, Protein structure prediction on 2D square HP lattice with revised fitness function. in 2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017. vol. 2017-January, Institute of Electrical and Electronics Engineers Inc., pp. 1732-1736, 2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017, Manipal, Mangalore, India, 13-09-17. https://doi.org/10.1109/ICACCI.2017.8126094

Protein structure prediction on 2D square HP lattice with revised fitness function. / Dubey, Sandhya Parasnath; Gopalakrishna Kini, N.; Balaji, S.; Sathish Kumar, M.

2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017. Vol. 2017-January Institute of Electrical and Electronics Engineers Inc., 2017. p. 1732-1736.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Dubey SP, Gopalakrishna Kini N, Balaji S, Sathish Kumar M. Protein structure prediction on 2D square HP lattice with revised fitness function. In 2017 International Conference on Advances in Computing, Communications and Informatics, ICACCI 2017. Vol. 2017-January. Institute of Electrical and Electronics Engineers Inc. 2017. p. 1732-1736 https://doi.org/10.1109/ICACCI.2017.8126094