2 Citations (Scopus)

Abstract

Among the nocardial species, Nocardia otitidiscaviarum (formerly Nocardia caviae) as causative agent of pulmonary disease is rarely reported even in immunocompromised individuals. We report 2 renal transplant recipients presenting with pleural effusion and acute respiratory distress syndrome owing to N. otitidiscaviarum. Culture of bronchial washings led to the diagnosis in both the cases and established importance of early bronchoscopy in diagnosing opportunistic pulmonary infections in immunocompromised individuals. Severe side effects of trimethoprim-sulfamethoxazole (TMP-SMX) in both the cases suggest the need to evolve safe and effective alternate drug regimens to treat nocardiosis.

Original languageEnglish
Pages (from-to)113-115
Number of pages3
JournalJournal of Bronchology
Volume15
Issue number2
DOIs
Publication statusPublished - 01-04-2008

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Nocardia Infections
Nocardia
Opportunistic Infections
Adult Respiratory Distress Syndrome
Sulfamethoxazole Drug Combination Trimethoprim
Bronchoscopy
Pleural Effusion
Lung Diseases
Kidney
Lung
Pharmaceutical Preparations
Transplant Recipients

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Cite this

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title = "Pulmonary nocardiosis owing to Nocardia otitidiscaviarum",
abstract = "Among the nocardial species, Nocardia otitidiscaviarum (formerly Nocardia caviae) as causative agent of pulmonary disease is rarely reported even in immunocompromised individuals. We report 2 renal transplant recipients presenting with pleural effusion and acute respiratory distress syndrome owing to N. otitidiscaviarum. Culture of bronchial washings led to the diagnosis in both the cases and established importance of early bronchoscopy in diagnosing opportunistic pulmonary infections in immunocompromised individuals. Severe side effects of trimethoprim-sulfamethoxazole (TMP-SMX) in both the cases suggest the need to evolve safe and effective alternate drug regimens to treat nocardiosis.",
author = "Karanam Gowrinath and Prabhu, {Attur Ravindra} and Indira Bairy and Prakash, {Peralam Yegneswaran} and Kiran Chawla and Baig, {Waqas Wahid}",
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Pulmonary nocardiosis owing to Nocardia otitidiscaviarum. / Gowrinath, Karanam; Prabhu, Attur Ravindra; Bairy, Indira; Prakash, Peralam Yegneswaran; Chawla, Kiran; Baig, Waqas Wahid.

In: Journal of Bronchology, Vol. 15, No. 2, 01.04.2008, p. 113-115.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Pulmonary nocardiosis owing to Nocardia otitidiscaviarum

AU - Gowrinath, Karanam

AU - Prabhu, Attur Ravindra

AU - Bairy, Indira

AU - Prakash, Peralam Yegneswaran

AU - Chawla, Kiran

AU - Baig, Waqas Wahid

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AB - Among the nocardial species, Nocardia otitidiscaviarum (formerly Nocardia caviae) as causative agent of pulmonary disease is rarely reported even in immunocompromised individuals. We report 2 renal transplant recipients presenting with pleural effusion and acute respiratory distress syndrome owing to N. otitidiscaviarum. Culture of bronchial washings led to the diagnosis in both the cases and established importance of early bronchoscopy in diagnosing opportunistic pulmonary infections in immunocompromised individuals. Severe side effects of trimethoprim-sulfamethoxazole (TMP-SMX) in both the cases suggest the need to evolve safe and effective alternate drug regimens to treat nocardiosis.

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