PUO – A rare (and forgotten) cause!

Preetam R. Acharya, R. Anand, Vishak K. Acharya, Ramesh Chandra Sahoo

Research output: Contribution to journalArticle

Abstract

Splenic tuberculosis is an extremely rare clinical entity and a frequently forgotten cause of pyrexia of unknown origin (PUO). We present the case of a 42 year old man who presented with fever of unknown origin. Ultrasonography revealed multiple hypoechoic areas within the spleen. As the abscesses did not respond to broad spectrum antibiotics splenectomy was done. The excised organ showed multiple cysts filled with pultaceous material. Histopathological examination revealed areas of granular caseating necrosis surrounded by epitheloid cells and Langhan’s type giant cells consistent with splenic tuberculosis. There was no evidence of a primary focus in the lungs or in any other organ. The presence of isolated tubercular foci in the spleen without any evidence of tuberculosis in lung or other extra-pulmonary site prompted us to report this case.

Original languageEnglish
Pages (from-to)66-68
Number of pages3
JournalJournal of Association of Physicians of India
Volume62
Issue numberOCT 2014
Publication statusPublished - 01-10-2014

Fingerprint

Splenic Tuberculosis
Fever
Lung
Langhans Giant Cells
Spleen
Fever of Unknown Origin
Splenectomy
Abscess
Cysts
Ultrasonography
Tuberculosis
Necrosis
Anti-Bacterial Agents

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Acharya, Preetam R. ; Anand, R. ; Acharya, Vishak K. ; Sahoo, Ramesh Chandra. / PUO – A rare (and forgotten) cause!. In: Journal of Association of Physicians of India. 2014 ; Vol. 62, No. OCT 2014. pp. 66-68.
@article{4e4fc7298fd4456581fdb1ce02217a65,
title = "PUO – A rare (and forgotten) cause!",
abstract = "Splenic tuberculosis is an extremely rare clinical entity and a frequently forgotten cause of pyrexia of unknown origin (PUO). We present the case of a 42 year old man who presented with fever of unknown origin. Ultrasonography revealed multiple hypoechoic areas within the spleen. As the abscesses did not respond to broad spectrum antibiotics splenectomy was done. The excised organ showed multiple cysts filled with pultaceous material. Histopathological examination revealed areas of granular caseating necrosis surrounded by epitheloid cells and Langhan’s type giant cells consistent with splenic tuberculosis. There was no evidence of a primary focus in the lungs or in any other organ. The presence of isolated tubercular foci in the spleen without any evidence of tuberculosis in lung or other extra-pulmonary site prompted us to report this case.",
author = "Acharya, {Preetam R.} and R. Anand and Acharya, {Vishak K.} and Sahoo, {Ramesh Chandra}",
year = "2014",
month = "10",
day = "1",
language = "English",
volume = "62",
pages = "66--68",
journal = "The Journal of the Association of Physicians of India",
issn = "0004-5772",
publisher = "Journal of Association of Physicians of India",
number = "OCT 2014",

}

Acharya, PR, Anand, R, Acharya, VK & Sahoo, RC 2014, 'PUO – A rare (and forgotten) cause!', Journal of Association of Physicians of India, vol. 62, no. OCT 2014, pp. 66-68.

PUO – A rare (and forgotten) cause! / Acharya, Preetam R.; Anand, R.; Acharya, Vishak K.; Sahoo, Ramesh Chandra.

In: Journal of Association of Physicians of India, Vol. 62, No. OCT 2014, 01.10.2014, p. 66-68.

Research output: Contribution to journalArticle

TY - JOUR

T1 - PUO – A rare (and forgotten) cause!

AU - Acharya, Preetam R.

AU - Anand, R.

AU - Acharya, Vishak K.

AU - Sahoo, Ramesh Chandra

PY - 2014/10/1

Y1 - 2014/10/1

N2 - Splenic tuberculosis is an extremely rare clinical entity and a frequently forgotten cause of pyrexia of unknown origin (PUO). We present the case of a 42 year old man who presented with fever of unknown origin. Ultrasonography revealed multiple hypoechoic areas within the spleen. As the abscesses did not respond to broad spectrum antibiotics splenectomy was done. The excised organ showed multiple cysts filled with pultaceous material. Histopathological examination revealed areas of granular caseating necrosis surrounded by epitheloid cells and Langhan’s type giant cells consistent with splenic tuberculosis. There was no evidence of a primary focus in the lungs or in any other organ. The presence of isolated tubercular foci in the spleen without any evidence of tuberculosis in lung or other extra-pulmonary site prompted us to report this case.

AB - Splenic tuberculosis is an extremely rare clinical entity and a frequently forgotten cause of pyrexia of unknown origin (PUO). We present the case of a 42 year old man who presented with fever of unknown origin. Ultrasonography revealed multiple hypoechoic areas within the spleen. As the abscesses did not respond to broad spectrum antibiotics splenectomy was done. The excised organ showed multiple cysts filled with pultaceous material. Histopathological examination revealed areas of granular caseating necrosis surrounded by epitheloid cells and Langhan’s type giant cells consistent with splenic tuberculosis. There was no evidence of a primary focus in the lungs or in any other organ. The presence of isolated tubercular foci in the spleen without any evidence of tuberculosis in lung or other extra-pulmonary site prompted us to report this case.

UR - http://www.scopus.com/inward/record.url?scp=84907485800&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907485800&partnerID=8YFLogxK

M3 - Article

VL - 62

SP - 66

EP - 68

JO - The Journal of the Association of Physicians of India

JF - The Journal of the Association of Physicians of India

SN - 0004-5772

IS - OCT 2014

ER -