Abstract
Radiation therapy is an important treatment modality for malignancies of the cervix, uterus, prostate, bladder, testes, and rectum. The incidence of clinically significant radiation-related complications is about 5-20%. Radiation insult to gastrointestinal tract includes damage to the small bowel, colon, and rectum. Predisposing risk factors such as previous surgery, hypertension, diabetes, smoking, hyperbaric oxygen increases the severity of damage as well as the use of other chemotherapeutic agents increases the sensitivity to radiation. Radiation-induced injury can be acute or chronic depending on the mitotic activity of intestinal tissue. Radiation enteritis is usually managed conservatively at the start, but surgery is indicated when complications arise. Hereby, we report a case of subacute intestinal obstruction after 3 weeks of radiotherapy.
| Original language | English |
|---|---|
| Pages (from-to) | 7-8 |
| Number of pages | 2 |
| Journal | Asian Journal of Pharmaceutical and Clinical Research |
| Volume | 10 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 01-01-2017 |
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All Science Journal Classification (ASJC) codes
- Pharmacology
- Pharmaceutical Science
- Pharmacology (medical)
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Radiation therapy-induced subacute intestinal obstruction. / Rupam, G.; Balaji, O.; Sereen, R. T.; Patil, Navin.
In: Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, No. 7, 01.01.2017, p. 7-8.Research output: Contribution to journal › Article
TY - JOUR
T1 - Radiation therapy-induced subacute intestinal obstruction
AU - Rupam, G.
AU - Balaji, O.
AU - Sereen, R. T.
AU - Patil, Navin
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Radiation therapy is an important treatment modality for malignancies of the cervix, uterus, prostate, bladder, testes, and rectum. The incidence of clinically significant radiation-related complications is about 5-20%. Radiation insult to gastrointestinal tract includes damage to the small bowel, colon, and rectum. Predisposing risk factors such as previous surgery, hypertension, diabetes, smoking, hyperbaric oxygen increases the severity of damage as well as the use of other chemotherapeutic agents increases the sensitivity to radiation. Radiation-induced injury can be acute or chronic depending on the mitotic activity of intestinal tissue. Radiation enteritis is usually managed conservatively at the start, but surgery is indicated when complications arise. Hereby, we report a case of subacute intestinal obstruction after 3 weeks of radiotherapy.
AB - Radiation therapy is an important treatment modality for malignancies of the cervix, uterus, prostate, bladder, testes, and rectum. The incidence of clinically significant radiation-related complications is about 5-20%. Radiation insult to gastrointestinal tract includes damage to the small bowel, colon, and rectum. Predisposing risk factors such as previous surgery, hypertension, diabetes, smoking, hyperbaric oxygen increases the severity of damage as well as the use of other chemotherapeutic agents increases the sensitivity to radiation. Radiation-induced injury can be acute or chronic depending on the mitotic activity of intestinal tissue. Radiation enteritis is usually managed conservatively at the start, but surgery is indicated when complications arise. Hereby, we report a case of subacute intestinal obstruction after 3 weeks of radiotherapy.
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UR - http://www.scopus.com/inward/citedby.url?scp=85021718105&partnerID=8YFLogxK
U2 - 10.22159/ajpcr.2017.v10i7.18520
DO - 10.22159/ajpcr.2017.v10i7.18520
M3 - Article
VL - 10
SP - 7
EP - 8
JO - Asian Journal of Pharmaceutical and Clinical Research
JF - Asian Journal of Pharmaceutical and Clinical Research
SN - 0974-2441
IS - 7
ER -