Radioprotective effect of Phyllanthus niruri on mouse chromosomes

P. Uma Devi, Ravindra Kamath, B. S S Rao

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Micronuclei (MN) induction in the mouse bone marrow polychromatic erythrocytes (PCE) and normochromatic erythrocytes (NCE) was studied 24 h after whole body exposure to 4 Gy of gamma radiation with or without a single intraperitoneal injection of 25 mg/kg to 150 mg/kg of 50% methanolic extract of Phyllanthus niruri (whole aerial part). The extract significantly reduced the radiation-induced MN induction in both PCE and NCE and increased the ratio of PCE to NCE. The effect increased linearly with extract dose from 25 to 125 mg/kg.

Original languageEnglish
Pages (from-to)1245-1247
Number of pages3
JournalCurrent Science
Volume78
Issue number10
Publication statusPublished - 25-05-2000

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Phyllanthus
Chromosomes
Erythrocytes
Radiation Dosage
Gamma Rays
Intraperitoneal Injections
Bone Marrow
Radiation

All Science Journal Classification (ASJC) codes

  • General

Cite this

Uma Devi, P. ; Kamath, Ravindra ; Rao, B. S S. / Radioprotective effect of Phyllanthus niruri on mouse chromosomes. In: Current Science. 2000 ; Vol. 78, No. 10. pp. 1245-1247.
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Uma Devi, P, Kamath, R & Rao, BSS 2000, 'Radioprotective effect of Phyllanthus niruri on mouse chromosomes', Current Science, vol. 78, no. 10, pp. 1245-1247.

Radioprotective effect of Phyllanthus niruri on mouse chromosomes. / Uma Devi, P.; Kamath, Ravindra; Rao, B. S S.

In: Current Science, Vol. 78, No. 10, 25.05.2000, p. 1245-1247.

Research output: Contribution to journalArticle

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