Radioprotective effect of Phyllanthus niruri on mouse chromosomes

P. Uma Devi, Ravindra Kamath, B. S S Rao

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19 Citations (Scopus)

Abstract

Micronuclei (MN) induction in the mouse bone marrow polychromatic erythrocytes (PCE) and normochromatic erythrocytes (NCE) was studied 24 h after whole body exposure to 4 Gy of gamma radiation with or without a single intraperitoneal injection of 25 mg/kg to 150 mg/kg of 50% methanolic extract of Phyllanthus niruri (whole aerial part). The extract significantly reduced the radiation-induced MN induction in both PCE and NCE and increased the ratio of PCE to NCE. The effect increased linearly with extract dose from 25 to 125 mg/kg.

Original languageEnglish
Pages (from-to)1245-1247
Number of pages3
JournalCurrent Science
Volume78
Issue number10
Publication statusPublished - 25-05-2000

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All Science Journal Classification (ASJC) codes

  • General

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