Abstract
Micronuclei (MN) induction in the mouse bone marrow polychromatic erythrocytes (PCE) and normochromatic erythrocytes (NCE) was studied 24 h after whole body exposure to 4 Gy of gamma radiation with or without a single intraperitoneal injection of 25 mg/kg to 150 mg/kg of 50% methanolic extract of Phyllanthus niruri (whole aerial part). The extract significantly reduced the radiation-induced MN induction in both PCE and NCE and increased the ratio of PCE to NCE. The effect increased linearly with extract dose from 25 to 125 mg/kg.
| Original language | English |
|---|---|
| Pages (from-to) | 1245-1247 |
| Number of pages | 3 |
| Journal | Current Science |
| Volume | 78 |
| Issue number | 10 |
| Publication status | Published - 25-05-2000 |
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All Science Journal Classification (ASJC) codes
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Radioprotective effect of Phyllanthus niruri on mouse chromosomes. / Uma Devi, P.; Kamath, Ravindra; Rao, B. S S.
In: Current Science, Vol. 78, No. 10, 25.05.2000, p. 1245-1247.Research output: Contribution to journal › Article
TY - JOUR
T1 - Radioprotective effect of Phyllanthus niruri on mouse chromosomes
AU - Uma Devi, P.
AU - Kamath, Ravindra
AU - Rao, B. S S
PY - 2000/5/25
Y1 - 2000/5/25
N2 - Micronuclei (MN) induction in the mouse bone marrow polychromatic erythrocytes (PCE) and normochromatic erythrocytes (NCE) was studied 24 h after whole body exposure to 4 Gy of gamma radiation with or without a single intraperitoneal injection of 25 mg/kg to 150 mg/kg of 50% methanolic extract of Phyllanthus niruri (whole aerial part). The extract significantly reduced the radiation-induced MN induction in both PCE and NCE and increased the ratio of PCE to NCE. The effect increased linearly with extract dose from 25 to 125 mg/kg.
AB - Micronuclei (MN) induction in the mouse bone marrow polychromatic erythrocytes (PCE) and normochromatic erythrocytes (NCE) was studied 24 h after whole body exposure to 4 Gy of gamma radiation with or without a single intraperitoneal injection of 25 mg/kg to 150 mg/kg of 50% methanolic extract of Phyllanthus niruri (whole aerial part). The extract significantly reduced the radiation-induced MN induction in both PCE and NCE and increased the ratio of PCE to NCE. The effect increased linearly with extract dose from 25 to 125 mg/kg.
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M3 - Article
VL - 78
SP - 1245
EP - 1247
JO - Current Science
JF - Current Science
SN - 0011-3891
IS - 10
ER -