Ranitidine-induced thrombocytopenia

A rare drug reaction

Amit V. Bangia, Narendra Kamath, Vidushi Mohan

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

H 2 antagonist ranitidine causing thrombocytopenia is a rare drug phenomenon. Here we present a case of 55 year old female of pustular psoriasis who presented with fever and vomiting. Patient. was started on roxithromycin, iv ondensetron, paracetamol and iv ranitidine. Complete blood count revealed neutrophilia with normal blood picture. However repeat investigations showed falling WBC and platelet count. After excluding other causes of pancytopenia we concluded that ranitidine was the cause for this atypical drug reaction, more so when the blood picture improved within 72 hrs of ranitidine withdrawal.

Original languageEnglish
Pages (from-to)76-77
Number of pages2
JournalIndian Journal of Pharmacology
Volume43
Issue number1
DOIs
Publication statusPublished - 01-02-2011
Externally publishedYes

Fingerprint

Ranitidine
Thrombocytopenia
Pharmaceutical Preparations
Accidental Falls
Roxithromycin
Pancytopenia
Blood Cell Count
Acetaminophen
Platelet Count
Psoriasis
Vomiting
Fever

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)

Cite this

Bangia, Amit V. ; Kamath, Narendra ; Mohan, Vidushi. / Ranitidine-induced thrombocytopenia : A rare drug reaction. In: Indian Journal of Pharmacology. 2011 ; Vol. 43, No. 1. pp. 76-77.
@article{48218146b45d42ca8e3c094c8ab6c14d,
title = "Ranitidine-induced thrombocytopenia: A rare drug reaction",
abstract = "H 2 antagonist ranitidine causing thrombocytopenia is a rare drug phenomenon. Here we present a case of 55 year old female of pustular psoriasis who presented with fever and vomiting. Patient. was started on roxithromycin, iv ondensetron, paracetamol and iv ranitidine. Complete blood count revealed neutrophilia with normal blood picture. However repeat investigations showed falling WBC and platelet count. After excluding other causes of pancytopenia we concluded that ranitidine was the cause for this atypical drug reaction, more so when the blood picture improved within 72 hrs of ranitidine withdrawal.",
author = "Bangia, {Amit V.} and Narendra Kamath and Vidushi Mohan",
year = "2011",
month = "2",
day = "1",
doi = "10.4103/0253-7613.75676",
language = "English",
volume = "43",
pages = "76--77",
journal = "Indian Journal of Pharmacology",
issn = "0253-7613",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "1",

}

Ranitidine-induced thrombocytopenia : A rare drug reaction. / Bangia, Amit V.; Kamath, Narendra; Mohan, Vidushi.

In: Indian Journal of Pharmacology, Vol. 43, No. 1, 01.02.2011, p. 76-77.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Ranitidine-induced thrombocytopenia

T2 - A rare drug reaction

AU - Bangia, Amit V.

AU - Kamath, Narendra

AU - Mohan, Vidushi

PY - 2011/2/1

Y1 - 2011/2/1

N2 - H 2 antagonist ranitidine causing thrombocytopenia is a rare drug phenomenon. Here we present a case of 55 year old female of pustular psoriasis who presented with fever and vomiting. Patient. was started on roxithromycin, iv ondensetron, paracetamol and iv ranitidine. Complete blood count revealed neutrophilia with normal blood picture. However repeat investigations showed falling WBC and platelet count. After excluding other causes of pancytopenia we concluded that ranitidine was the cause for this atypical drug reaction, more so when the blood picture improved within 72 hrs of ranitidine withdrawal.

AB - H 2 antagonist ranitidine causing thrombocytopenia is a rare drug phenomenon. Here we present a case of 55 year old female of pustular psoriasis who presented with fever and vomiting. Patient. was started on roxithromycin, iv ondensetron, paracetamol and iv ranitidine. Complete blood count revealed neutrophilia with normal blood picture. However repeat investigations showed falling WBC and platelet count. After excluding other causes of pancytopenia we concluded that ranitidine was the cause for this atypical drug reaction, more so when the blood picture improved within 72 hrs of ranitidine withdrawal.

UR - http://www.scopus.com/inward/record.url?scp=78951484865&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78951484865&partnerID=8YFLogxK

U2 - 10.4103/0253-7613.75676

DO - 10.4103/0253-7613.75676

M3 - Article

VL - 43

SP - 76

EP - 77

JO - Indian Journal of Pharmacology

JF - Indian Journal of Pharmacology

SN - 0253-7613

IS - 1

ER -