Peripheral giant cell granuloma is an inflammatory hyperplastic lesion that commonly occurs on peripheral tissues like gingiva, periodontal ligaments or alveolar mucosa. Clinically it is only seen in gingiva, particularly between the first permanent molars and incisors. It manifests itself as a benign tumor consisting of multinucleated giant cells. This article reports a case of peripheral giant cell granuloma in the left mandibular premolar region in a 34-year-old man. The lesion was excised and sent for histopathological examination, and was diagnosed as peripheral giant cell granuloma. The lesion was recurrent. This case report shows the importance of confirming the diagnosis of the lesion by histopathological examination. Peripheral giant cell granuloma is a reactive lesion that shows a rapid growth rate and can cause minor tooth movement. As the name suggests, there is no bony involvement and the enlargement is a soft tissue extension. Early conservative management will reduce the risk of tooth loss.
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