The floating drug delivery system (FDDS) design appears to be one of the most effective and rational approaches for the controlled oral drug delivery. This FDDS appears to have a distinct advantage in delivering the drugs that are absorbed mainly in the upper part of the GI tract and drugs having stability and solubility problem in the lower part of the intestine. This area of research therefore should be aimed at developing the dosage forms to increase the pharmacokinetic profile of the drugs. There are various natural polymers and gums, which need to be explored to find their use in the designing of floating dosage forms, which have a high potential for the commercialization of the drugs. An attempt has been made in this review article to introduce the readers to the current technology development in floating drug delivery system.
|Number of pages||8|
|Publication status||Published - 2006|
Shirwaikar, A. A., Kumar, S. M. R., Jacob, S., Rashi, W., & Ravi, K. (2006). Recent developments in floating drug delivery systems for gastric retention of drugs, an overview. Indian Drugs, 43(9), 697-704.