Recurrent giant myofibroblastoma of a female breast leading to a diagnostic dilemma: A lesson learnt!

Research output: Contribution to journalArticle

Abstract

Myofibroblastoma (MFB) is a rare benign mesenchymal tumor of the breast commonly reported in males. It is a spindle cell neoplasm exhibiting myofibroblastic differentiation with characteristic immunohistochemical staining. We report the case of a 68-year-old postmenopausal lady who had undergone left breast lump excision 4 months back that was reported as malignant, now presenting with a rapidly growing hard mass in the same breast with no palpable axillary lymph nodes. Metastatic work-up was negative and she was planned for a lumpectomy, frozen section and if malignant, proceed to a modified radical mastectomy. Frozen section revealed a benign tumor. The final histopathology was reported to be MFB of the breast. The purpose of this report is to highlight that MFB can also occur in postmenopausal women, can recur and the diagnostic dilemma of this condition, which could have led to a mastectomy, but was avoided.

Original languageEnglish
Pages (from-to)210-213
Number of pages4
JournalKuwait Medical Journal
Volume51
Issue number2
Publication statusPublished - 06-2019

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Muscle Tissue Neoplasms
Breast
Frozen Sections
Modified Radical Mastectomy
Segmental Mastectomy
Mastectomy
Neoplasms
Lymph Nodes
Staining and Labeling
Breast Neoplasms

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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abstract = "Myofibroblastoma (MFB) is a rare benign mesenchymal tumor of the breast commonly reported in males. It is a spindle cell neoplasm exhibiting myofibroblastic differentiation with characteristic immunohistochemical staining. We report the case of a 68-year-old postmenopausal lady who had undergone left breast lump excision 4 months back that was reported as malignant, now presenting with a rapidly growing hard mass in the same breast with no palpable axillary lymph nodes. Metastatic work-up was negative and she was planned for a lumpectomy, frozen section and if malignant, proceed to a modified radical mastectomy. Frozen section revealed a benign tumor. The final histopathology was reported to be MFB of the breast. The purpose of this report is to highlight that MFB can also occur in postmenopausal women, can recur and the diagnostic dilemma of this condition, which could have led to a mastectomy, but was avoided.",
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Recurrent giant myofibroblastoma of a female breast leading to a diagnostic dilemma : A lesson learnt! / Ballal, Devesh; Rodrigues, Gabriel; Pai, Kantilatha.

In: Kuwait Medical Journal, Vol. 51, No. 2, 06.2019, p. 210-213.

Research output: Contribution to journalArticle

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