Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma

U. V. Singh, N. Udupa

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Inclusion complex of plumbagin was prepared with betacyclodextrin employing neutralization method. The toxicity of the drug was reduced and the antitumor efficacy was enhanced on complexation with betacyclodextrin.

Original languageEnglish
Pages (from-to)171-175
Number of pages5
JournalIndian Journal of Physiology and Pharmacology
Volume41
Issue number2
Publication statusPublished - 04-1997

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Drug-Related Side Effects and Adverse Reactions
Ascites
Carcinoma
plumbagin

All Science Journal Classification (ASJC) codes

  • Physiology
  • Pharmacology
  • Physiology (medical)

Cite this

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abstract = "Inclusion complex of plumbagin was prepared with betacyclodextrin employing neutralization method. The toxicity of the drug was reduced and the antitumor efficacy was enhanced on complexation with betacyclodextrin.",
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