Reference equations for 6-min walk test in healthy Indian subjects (25-80 years)

Ramanathan Palaniappan Ramanathan, Baskaran Chandrasekaran

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background: Six-min walk test (6MWT), a simple functional capacity evaluation tool used globally to determine the prognosis and effectiveness of any therapeutic/medical intervention. However, variability in reference equations derived from western population (due to racial and ethnicity variations) hinders from adequate use of 6MWT clinically. Further, there are no valid Indian studies that predict reference values for 6-min walk distance (6MWD) in healthy Indian normal. Objective: We aimed for framing individualized reference equations for 6MWT in healthy Indian population. Materials and Methods: Anthropometric variables (age, weight, height, and body mass index (BMI)) and 6-min walk in a 30 m corridor were evaluated in 125 subjects (67 females) in a cross-sectional trial. Results: 6MWD significantly correlated with age (r = -0.29), height (r = 0.393), weight (r = 0.08), and BMI (r = -0.17). The gender specific reference equations for healthy Indian individuals were: (1) Males: 561.022 - (2.507 × age [years]) + (1.505 × weight [kg]) - (0.055 × height [cm]). R2 = 0.288. (2) Indian females: 30.325 - (0.809 × age [years]) - (2.074 × weight [kg]) + (4.235 × height [cm]). R2 = 0.272. Though the equations possess a small coefficient of determination and larger standard error estimate, the former applicability to Indian population is justified. Conclusion: These reference equations are probably most appropriate for evaluating the walked capacity of Indian patients with chronic diseases.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalLung India
Volume31
Issue number1
DOIs
Publication statusPublished - 01-01-2014

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Healthy Volunteers
Weights and Measures
Body Mass Index
Population
Reference Values
Chronic Disease
Walk Test
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Cite this

Ramanathan, Ramanathan Palaniappan ; Chandrasekaran, Baskaran. / Reference equations for 6-min walk test in healthy Indian subjects (25-80 years). In: Lung India. 2014 ; Vol. 31, No. 1. pp. 35-38.
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Reference equations for 6-min walk test in healthy Indian subjects (25-80 years). / Ramanathan, Ramanathan Palaniappan; Chandrasekaran, Baskaran.

In: Lung India, Vol. 31, No. 1, 01.01.2014, p. 35-38.

Research output: Contribution to journalArticle

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N2 - Background: Six-min walk test (6MWT), a simple functional capacity evaluation tool used globally to determine the prognosis and effectiveness of any therapeutic/medical intervention. However, variability in reference equations derived from western population (due to racial and ethnicity variations) hinders from adequate use of 6MWT clinically. Further, there are no valid Indian studies that predict reference values for 6-min walk distance (6MWD) in healthy Indian normal. Objective: We aimed for framing individualized reference equations for 6MWT in healthy Indian population. Materials and Methods: Anthropometric variables (age, weight, height, and body mass index (BMI)) and 6-min walk in a 30 m corridor were evaluated in 125 subjects (67 females) in a cross-sectional trial. Results: 6MWD significantly correlated with age (r = -0.29), height (r = 0.393), weight (r = 0.08), and BMI (r = -0.17). The gender specific reference equations for healthy Indian individuals were: (1) Males: 561.022 - (2.507 × age [years]) + (1.505 × weight [kg]) - (0.055 × height [cm]). R2 = 0.288. (2) Indian females: 30.325 - (0.809 × age [years]) - (2.074 × weight [kg]) + (4.235 × height [cm]). R2 = 0.272. Though the equations possess a small coefficient of determination and larger standard error estimate, the former applicability to Indian population is justified. Conclusion: These reference equations are probably most appropriate for evaluating the walked capacity of Indian patients with chronic diseases.

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