Regiospecific reaction

Synthesis and biological assay of some sydnone and triazole-containing Mannich derivatives

Balakrishna Kalluraya, Ganesha Rai, Satheesha Rai, Shalini Shenoy

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Condensation of 3-substituted-4-amino-1,2,4-triazole-5-thiones 3 with 3-aryl-sydnone-4-carboxaldehyde 5 afforded a series of Schiff's bases 6. These Schiff's bases underwent Mannich reaction regiospecifically with morpholine and formaldehyde to give Mannich bases 7. The new compounds were characterized by spectral and analytical data. Biological screening results showed promising antibacterial and antifungal activities for these compounds.

Original languageEnglish
Pages (from-to)127-130
Number of pages4
JournalIndian Journal of Heterocyclic Chemistry
Volume14
Issue number2
Publication statusPublished - 01-10-2004

Fingerprint

Sydnones
Triazoles
Schiff Bases
Biological Assay
Assays
Mannich Bases
Derivatives
Thiones
Formaldehyde
Condensation
Screening

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

Kalluraya, Balakrishna ; Rai, Ganesha ; Rai, Satheesha ; Shenoy, Shalini. / Regiospecific reaction : Synthesis and biological assay of some sydnone and triazole-containing Mannich derivatives. In: Indian Journal of Heterocyclic Chemistry. 2004 ; Vol. 14, No. 2. pp. 127-130.
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Regiospecific reaction : Synthesis and biological assay of some sydnone and triazole-containing Mannich derivatives. / Kalluraya, Balakrishna; Rai, Ganesha; Rai, Satheesha; Shenoy, Shalini.

In: Indian Journal of Heterocyclic Chemistry, Vol. 14, No. 2, 01.10.2004, p. 127-130.

Research output: Contribution to journalArticle

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AU - Rai, Satheesha

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