Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia

Ashley Ross, Thomas W. McLean, Rebecca Farber, R. Grey Weaver, Allen Chauvenet, Laurence B. Givner, Avinash K. Shetty

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Serious ocular disease following varicella (chickenpox) is rare in children. In addition, retinitis in children with hematologic malignancies may present a difficult diagnostic challenge because infectious retinitis may mimic leukemic involvement of the eye. We report a 7-year-old patient with T-cell acute lymphoblastic leukemia in remission who presented with visual complaints 2 weeks after developing chickenpox. Ophthalmologic evaluation revealed acute retinitis in the right eye. Prolonged therapy with acyclovir resulted in near complete recovery. Early diagnosis of VZV retinopathy and aggressive antiviral treatment is critical to prevent acute and long-term ocular sequelae.

Original languageEnglish
Pages (from-to)191-194
Number of pages4
JournalPediatric Blood and Cancer
Volume45
Issue number2
DOIs
Publication statusPublished - 01-08-2005
Externally publishedYes

Fingerprint

Retinitis
Chickenpox
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Acyclovir
Eye Diseases
Hematologic Neoplasms
Antiviral Agents
Early Diagnosis
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Cite this

Ross, A., McLean, T. W., Farber, R., Weaver, R. G., Chauvenet, A., Givner, L. B., & Shetty, A. K. (2005). Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia. Pediatric Blood and Cancer, 45(2), 191-194. https://doi.org/10.1002/pbc.20118
Ross, Ashley ; McLean, Thomas W. ; Farber, Rebecca ; Weaver, R. Grey ; Chauvenet, Allen ; Givner, Laurence B. ; Shetty, Avinash K. / Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia. In: Pediatric Blood and Cancer. 2005 ; Vol. 45, No. 2. pp. 191-194.
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Ross, A, McLean, TW, Farber, R, Weaver, RG, Chauvenet, A, Givner, LB & Shetty, AK 2005, 'Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia', Pediatric Blood and Cancer, vol. 45, no. 2, pp. 191-194. https://doi.org/10.1002/pbc.20118

Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia. / Ross, Ashley; McLean, Thomas W.; Farber, Rebecca; Weaver, R. Grey; Chauvenet, Allen; Givner, Laurence B.; Shetty, Avinash K.

In: Pediatric Blood and Cancer, Vol. 45, No. 2, 01.08.2005, p. 191-194.

Research output: Contribution to journalArticle

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Ross A, McLean TW, Farber R, Weaver RG, Chauvenet A, Givner LB et al. Retinitis following varicella in a vaccinated child with acute lymphoblastic leukemia. Pediatric Blood and Cancer. 2005 Aug 1;45(2):191-194. https://doi.org/10.1002/pbc.20118