Rhabdomyoma of larynx - A diagnaostic dilemma

S. Vijendra Shenoy, A. Raghavendra Rao, Vishnu Prasad, Supriya Miriam Kuriakose

Research output: Contribution to journalArticle

Abstract

Introduction: Rhabdomyomas of the head and neck are unusual. Extracardiac rhabdomyoma is a rare benign tumor of striated muscle origin that is found in adults and children. We report a case of rhabdomyoma of the larynx, which presented a diagnostic dilemma. Case report: We report an uncommon case of a 50-year-old man, who presented with change in voice for two years. Endoscopic examination of the larynx revealed a smooth mass covered by intact mucosa involving the right aryepiglottic fold and a false vocal cord with restricted right vocal cord mobility. Biopsy from the lesion revealed a diagnosis of squamous cell carcinoma. The patient underwent total laryngectomy. To our surprise, histologic examination and immunohistochemical diagnosis proved it to be rhabdomyoma of the adult type with no evidence of malignancy. Discussion: Most extracardiac rhabdomyomas arise from the pharyngeal constrictor muscles, the floor of the mouth, or the base of the tongue. Rarely, rhabdomyomas may arise from the larynx. Histologic and immunohistochemical analysis is essential for diagnosis. Treatment of rhabdomyoma consists primarily of complete excision with preservation of the surrounding tissues. Conclusion: Our case demonstrates various differential diagnoses possible in laryngeal neoplasms. It also shows that immunocytochemistry plays an important role in differential diagnosis.

Original languageEnglish
Pages (from-to)217-220
Number of pages4
JournalEgyptian Journal of Ear, Nose, Throat and Allied Sciences
Volume14
Issue number3
DOIs
Publication statusPublished - 01-11-2013

Fingerprint

Rhabdomyoma
Larynx
Vocal Cords
Differential Diagnosis
Pharyngeal Muscles
Tissue Preservation
Mouth Floor
Laryngectomy
Laryngeal Neoplasms
Striated Muscle
Tongue
Squamous Cell Carcinoma
Neoplasms
Mucous Membrane
Neck
Immunohistochemistry
Head
Biopsy

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

Cite this

Vijendra Shenoy, S. ; Raghavendra Rao, A. ; Prasad, Vishnu ; Kuriakose, Supriya Miriam. / Rhabdomyoma of larynx - A diagnaostic dilemma. In: Egyptian Journal of Ear, Nose, Throat and Allied Sciences. 2013 ; Vol. 14, No. 3. pp. 217-220.
@article{d9de4b4f2ab24be4a44407003477fa1c,
title = "Rhabdomyoma of larynx - A diagnaostic dilemma",
abstract = "Introduction: Rhabdomyomas of the head and neck are unusual. Extracardiac rhabdomyoma is a rare benign tumor of striated muscle origin that is found in adults and children. We report a case of rhabdomyoma of the larynx, which presented a diagnostic dilemma. Case report: We report an uncommon case of a 50-year-old man, who presented with change in voice for two years. Endoscopic examination of the larynx revealed a smooth mass covered by intact mucosa involving the right aryepiglottic fold and a false vocal cord with restricted right vocal cord mobility. Biopsy from the lesion revealed a diagnosis of squamous cell carcinoma. The patient underwent total laryngectomy. To our surprise, histologic examination and immunohistochemical diagnosis proved it to be rhabdomyoma of the adult type with no evidence of malignancy. Discussion: Most extracardiac rhabdomyomas arise from the pharyngeal constrictor muscles, the floor of the mouth, or the base of the tongue. Rarely, rhabdomyomas may arise from the larynx. Histologic and immunohistochemical analysis is essential for diagnosis. Treatment of rhabdomyoma consists primarily of complete excision with preservation of the surrounding tissues. Conclusion: Our case demonstrates various differential diagnoses possible in laryngeal neoplasms. It also shows that immunocytochemistry plays an important role in differential diagnosis.",
author = "{Vijendra Shenoy}, S. and {Raghavendra Rao}, A. and Vishnu Prasad and Kuriakose, {Supriya Miriam}",
year = "2013",
month = "11",
day = "1",
doi = "10.1016/j.ejenta.2013.06.002",
language = "English",
volume = "14",
pages = "217--220",
journal = "Egyptian Journal of Ear, Nose, Throat and Allied Sciences",
issn = "2090-0740",
publisher = "Egyptian Society of Ear, Nose, Throat and Allied Sciences",
number = "3",

}

Rhabdomyoma of larynx - A diagnaostic dilemma. / Vijendra Shenoy, S.; Raghavendra Rao, A.; Prasad, Vishnu; Kuriakose, Supriya Miriam.

In: Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Vol. 14, No. 3, 01.11.2013, p. 217-220.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Rhabdomyoma of larynx - A diagnaostic dilemma

AU - Vijendra Shenoy, S.

AU - Raghavendra Rao, A.

AU - Prasad, Vishnu

AU - Kuriakose, Supriya Miriam

PY - 2013/11/1

Y1 - 2013/11/1

N2 - Introduction: Rhabdomyomas of the head and neck are unusual. Extracardiac rhabdomyoma is a rare benign tumor of striated muscle origin that is found in adults and children. We report a case of rhabdomyoma of the larynx, which presented a diagnostic dilemma. Case report: We report an uncommon case of a 50-year-old man, who presented with change in voice for two years. Endoscopic examination of the larynx revealed a smooth mass covered by intact mucosa involving the right aryepiglottic fold and a false vocal cord with restricted right vocal cord mobility. Biopsy from the lesion revealed a diagnosis of squamous cell carcinoma. The patient underwent total laryngectomy. To our surprise, histologic examination and immunohistochemical diagnosis proved it to be rhabdomyoma of the adult type with no evidence of malignancy. Discussion: Most extracardiac rhabdomyomas arise from the pharyngeal constrictor muscles, the floor of the mouth, or the base of the tongue. Rarely, rhabdomyomas may arise from the larynx. Histologic and immunohistochemical analysis is essential for diagnosis. Treatment of rhabdomyoma consists primarily of complete excision with preservation of the surrounding tissues. Conclusion: Our case demonstrates various differential diagnoses possible in laryngeal neoplasms. It also shows that immunocytochemistry plays an important role in differential diagnosis.

AB - Introduction: Rhabdomyomas of the head and neck are unusual. Extracardiac rhabdomyoma is a rare benign tumor of striated muscle origin that is found in adults and children. We report a case of rhabdomyoma of the larynx, which presented a diagnostic dilemma. Case report: We report an uncommon case of a 50-year-old man, who presented with change in voice for two years. Endoscopic examination of the larynx revealed a smooth mass covered by intact mucosa involving the right aryepiglottic fold and a false vocal cord with restricted right vocal cord mobility. Biopsy from the lesion revealed a diagnosis of squamous cell carcinoma. The patient underwent total laryngectomy. To our surprise, histologic examination and immunohistochemical diagnosis proved it to be rhabdomyoma of the adult type with no evidence of malignancy. Discussion: Most extracardiac rhabdomyomas arise from the pharyngeal constrictor muscles, the floor of the mouth, or the base of the tongue. Rarely, rhabdomyomas may arise from the larynx. Histologic and immunohistochemical analysis is essential for diagnosis. Treatment of rhabdomyoma consists primarily of complete excision with preservation of the surrounding tissues. Conclusion: Our case demonstrates various differential diagnoses possible in laryngeal neoplasms. It also shows that immunocytochemistry plays an important role in differential diagnosis.

UR - http://www.scopus.com/inward/record.url?scp=84942077184&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84942077184&partnerID=8YFLogxK

U2 - 10.1016/j.ejenta.2013.06.002

DO - 10.1016/j.ejenta.2013.06.002

M3 - Article

VL - 14

SP - 217

EP - 220

JO - Egyptian Journal of Ear, Nose, Throat and Allied Sciences

JF - Egyptian Journal of Ear, Nose, Throat and Allied Sciences

SN - 2090-0740

IS - 3

ER -