Abstract

Objectives: The present study was undertaken to study the maternal risk factors for preterm birth (PTB) and low birth weight (LBW) with a special emphasis on assessing the proportions of maternal genitourinary and periodontal infections among Indian women and their association with adverse pregnancy outcomes. .Methods: A hospital-based prospective study comprising 790 pregnant women visiting the obstetrics clinic for a routine antenatal check-up was undertaken. Once recruited, all study participants underwent clinical and microbiological investigations for genitourinary infections followed by a dental check-up for the presence of periodontitis. The study participants were followed up until their delivery to record the pregnancy outcomes. Infectious and non-infectious risk factors for PTB and LBW were assessed using univariate and multivariate Cox regression analysis. Independent risk factors for PTB and LBW were reported in terms of adjusted relative risk (ARR) with the 95% confidence interval (CI). .Results: Rates of PTB and LBW in the study population were 7.6% and 11.4%, respectively. Previous preterm delivery (ARR, 5.37; 95% CI, 1.5 to 19.1), periodontitis (ARR, 2.39; 95% CI, 1.1 to 4.9), Oligohydramnios (ARR, 5.23; 95% CI, 2.4 to 11.5), presence of Nugent's intermediate vaginal flora (ARR, 2.75; 95% CI, 1.4 to 5.1), gestational diabetes mellitus (ARR, 2.91; 95% CI, 1.0 to 8.3), and maternal height <1.50 m (ARR, 2.21; 95% CI, 1.1 to 4.1) were risk factors for PTB, while periodontitis (ARR, 3.38; 95% CI, 1.6 to 6.9), gestational hypertension (ARR, 3.70; 95% CI, 1.3 to 10.8), maternal height <1.50 m (ARR, 2.66; 95% CI, 1.3 to 5.1) and genital infection during later stages of pregnancy (ARR, 2.79; 95% CI, 1.2 to 6.1) were independent risk factors for LBW. Conclusions: Our study findings underscore the need to consider screening for potential genitourinary and periodontal infections during routine antenatal care in developing countries.

Original languageEnglish
Pages (from-to)165-175
Number of pages11
JournalJournal of Preventive Medicine and Public Health
Volume49
Issue number3
DOIs
Publication statusPublished - 01-05-2016

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Premature Birth
Low Birth Weight Infant
Pregnant Women
Prospective Studies
Confidence Intervals
Periodontitis
Mothers
Pregnancy Outcome
Infection
Oligohydramnios
Pregnancy Induced Hypertension
Prenatal Care
Gestational Diabetes
Developing Countries
Obstetrics
Tooth
Regression Analysis
Pregnancy

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

Cite this

@article{a09b08b907804cd19858761497e2b5cf,
title = "Risk factors for preterm birth and low birth weight among pregnant Indian women: A hospital-based prospective study",
abstract = "Objectives: The present study was undertaken to study the maternal risk factors for preterm birth (PTB) and low birth weight (LBW) with a special emphasis on assessing the proportions of maternal genitourinary and periodontal infections among Indian women and their association with adverse pregnancy outcomes. .Methods: A hospital-based prospective study comprising 790 pregnant women visiting the obstetrics clinic for a routine antenatal check-up was undertaken. Once recruited, all study participants underwent clinical and microbiological investigations for genitourinary infections followed by a dental check-up for the presence of periodontitis. The study participants were followed up until their delivery to record the pregnancy outcomes. Infectious and non-infectious risk factors for PTB and LBW were assessed using univariate and multivariate Cox regression analysis. Independent risk factors for PTB and LBW were reported in terms of adjusted relative risk (ARR) with the 95{\%} confidence interval (CI). .Results: Rates of PTB and LBW in the study population were 7.6{\%} and 11.4{\%}, respectively. Previous preterm delivery (ARR, 5.37; 95{\%} CI, 1.5 to 19.1), periodontitis (ARR, 2.39; 95{\%} CI, 1.1 to 4.9), Oligohydramnios (ARR, 5.23; 95{\%} CI, 2.4 to 11.5), presence of Nugent's intermediate vaginal flora (ARR, 2.75; 95{\%} CI, 1.4 to 5.1), gestational diabetes mellitus (ARR, 2.91; 95{\%} CI, 1.0 to 8.3), and maternal height <1.50 m (ARR, 2.21; 95{\%} CI, 1.1 to 4.1) were risk factors for PTB, while periodontitis (ARR, 3.38; 95{\%} CI, 1.6 to 6.9), gestational hypertension (ARR, 3.70; 95{\%} CI, 1.3 to 10.8), maternal height <1.50 m (ARR, 2.66; 95{\%} CI, 1.3 to 5.1) and genital infection during later stages of pregnancy (ARR, 2.79; 95{\%} CI, 1.2 to 6.1) were independent risk factors for LBW. Conclusions: Our study findings underscore the need to consider screening for potential genitourinary and periodontal infections during routine antenatal care in developing countries.",
author = "Chaitanya Tellapragada and Eshwara, {Vandana Kalwaje} and Parvati Bhat and Shashidhar Acharya and Asha Kamath and Shashikala Bhat and Chythra Rao and Sathisha Nayak and Chiranjay Mukhopadhyay",
year = "2016",
month = "5",
day = "1",
doi = "10.3961/jpmph.16.022",
language = "English",
volume = "49",
pages = "165--175",
journal = "Journal of Preventive Medicine and Public Health",
issn = "1975-8375",
publisher = "Korean Society for Preventive Medicine",
number = "3",

}

TY - JOUR

T1 - Risk factors for preterm birth and low birth weight among pregnant Indian women

T2 - A hospital-based prospective study

AU - Tellapragada, Chaitanya

AU - Eshwara, Vandana Kalwaje

AU - Bhat, Parvati

AU - Acharya, Shashidhar

AU - Kamath, Asha

AU - Bhat, Shashikala

AU - Rao, Chythra

AU - Nayak, Sathisha

AU - Mukhopadhyay, Chiranjay

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Objectives: The present study was undertaken to study the maternal risk factors for preterm birth (PTB) and low birth weight (LBW) with a special emphasis on assessing the proportions of maternal genitourinary and periodontal infections among Indian women and their association with adverse pregnancy outcomes. .Methods: A hospital-based prospective study comprising 790 pregnant women visiting the obstetrics clinic for a routine antenatal check-up was undertaken. Once recruited, all study participants underwent clinical and microbiological investigations for genitourinary infections followed by a dental check-up for the presence of periodontitis. The study participants were followed up until their delivery to record the pregnancy outcomes. Infectious and non-infectious risk factors for PTB and LBW were assessed using univariate and multivariate Cox regression analysis. Independent risk factors for PTB and LBW were reported in terms of adjusted relative risk (ARR) with the 95% confidence interval (CI). .Results: Rates of PTB and LBW in the study population were 7.6% and 11.4%, respectively. Previous preterm delivery (ARR, 5.37; 95% CI, 1.5 to 19.1), periodontitis (ARR, 2.39; 95% CI, 1.1 to 4.9), Oligohydramnios (ARR, 5.23; 95% CI, 2.4 to 11.5), presence of Nugent's intermediate vaginal flora (ARR, 2.75; 95% CI, 1.4 to 5.1), gestational diabetes mellitus (ARR, 2.91; 95% CI, 1.0 to 8.3), and maternal height <1.50 m (ARR, 2.21; 95% CI, 1.1 to 4.1) were risk factors for PTB, while periodontitis (ARR, 3.38; 95% CI, 1.6 to 6.9), gestational hypertension (ARR, 3.70; 95% CI, 1.3 to 10.8), maternal height <1.50 m (ARR, 2.66; 95% CI, 1.3 to 5.1) and genital infection during later stages of pregnancy (ARR, 2.79; 95% CI, 1.2 to 6.1) were independent risk factors for LBW. Conclusions: Our study findings underscore the need to consider screening for potential genitourinary and periodontal infections during routine antenatal care in developing countries.

AB - Objectives: The present study was undertaken to study the maternal risk factors for preterm birth (PTB) and low birth weight (LBW) with a special emphasis on assessing the proportions of maternal genitourinary and periodontal infections among Indian women and their association with adverse pregnancy outcomes. .Methods: A hospital-based prospective study comprising 790 pregnant women visiting the obstetrics clinic for a routine antenatal check-up was undertaken. Once recruited, all study participants underwent clinical and microbiological investigations for genitourinary infections followed by a dental check-up for the presence of periodontitis. The study participants were followed up until their delivery to record the pregnancy outcomes. Infectious and non-infectious risk factors for PTB and LBW were assessed using univariate and multivariate Cox regression analysis. Independent risk factors for PTB and LBW were reported in terms of adjusted relative risk (ARR) with the 95% confidence interval (CI). .Results: Rates of PTB and LBW in the study population were 7.6% and 11.4%, respectively. Previous preterm delivery (ARR, 5.37; 95% CI, 1.5 to 19.1), periodontitis (ARR, 2.39; 95% CI, 1.1 to 4.9), Oligohydramnios (ARR, 5.23; 95% CI, 2.4 to 11.5), presence of Nugent's intermediate vaginal flora (ARR, 2.75; 95% CI, 1.4 to 5.1), gestational diabetes mellitus (ARR, 2.91; 95% CI, 1.0 to 8.3), and maternal height <1.50 m (ARR, 2.21; 95% CI, 1.1 to 4.1) were risk factors for PTB, while periodontitis (ARR, 3.38; 95% CI, 1.6 to 6.9), gestational hypertension (ARR, 3.70; 95% CI, 1.3 to 10.8), maternal height <1.50 m (ARR, 2.66; 95% CI, 1.3 to 5.1) and genital infection during later stages of pregnancy (ARR, 2.79; 95% CI, 1.2 to 6.1) were independent risk factors for LBW. Conclusions: Our study findings underscore the need to consider screening for potential genitourinary and periodontal infections during routine antenatal care in developing countries.

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U2 - 10.3961/jpmph.16.022

DO - 10.3961/jpmph.16.022

M3 - Article

VL - 49

SP - 165

EP - 175

JO - Journal of Preventive Medicine and Public Health

JF - Journal of Preventive Medicine and Public Health

SN - 1975-8375

IS - 3

ER -