Role of hypomagnesaemia in acute kidney injury

Ventakarakesh Chintala, Venkataraya M. Prabhu, Manaswitha Boyanagari, Ajay N. Bhat

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Introduction: Acute Kidney Injury (AKI) is a common problem with various causes and consequences like electrolyte disturbances in the form of hypocalcaemia, hypokalemia, hyperkalemia depending on the phase. Serum magnesium concentration of <1.5 meq/L is defined as hypomagnesaemia and is one of the common electrolyte abnormality. Serum magnesium levels are not routinely done in AKI cases. Aim: The aim of our study was to assess the role of hypomagnesaemia as a risk factor for non recovery of AKI. Materials and Methods: A cross-sectional study was conducted between July 2014 and August 2015 with a sample of 100 patients. The decrease in magnesium <1.5 meq/L was defined as hypomagnesaemia. AKI was defined as per KDIGO criteria. Day 1, day 3 and day 6 magnesium levels were measured. Results: Prevalence of hypomagnesaemia was 69%, 43% and 27% on day 1, day 3 and day 6 respectively. It was observed that hypomagnesaemia on day 1 was significantly associated with recovery of AKI (p=0.004). Conclusion: Prevalence of hypomagnesaemia was significantly higher in AKI patients and hypomagnesaemia on day 1 was associated with recovery. However, magnesium levels on day 3 and day 6 had no significant correlation with the renal function in AKI.

Original languageEnglish
Pages (from-to)OC08-OC10
JournalJournal of Clinical and Diagnostic Research
Volume12
Issue number3
DOIs
Publication statusPublished - 01-03-2018
Externally publishedYes

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Acute Kidney Injury
Magnesium
Recovery
Electrolytes
Hyperkalemia
Hypokalemia
Hypocalcemia
Serum
Cross-Sectional Studies
Kidney

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

Chintala, Ventakarakesh ; Prabhu, Venkataraya M. ; Boyanagari, Manaswitha ; Bhat, Ajay N. / Role of hypomagnesaemia in acute kidney injury. In: Journal of Clinical and Diagnostic Research. 2018 ; Vol. 12, No. 3. pp. OC08-OC10.
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Chintala, V, Prabhu, VM, Boyanagari, M & Bhat, AN 2018, 'Role of hypomagnesaemia in acute kidney injury', Journal of Clinical and Diagnostic Research, vol. 12, no. 3, pp. OC08-OC10. https://doi.org/10.7860/JCDR/2018/28073.11329

Role of hypomagnesaemia in acute kidney injury. / Chintala, Ventakarakesh; Prabhu, Venkataraya M.; Boyanagari, Manaswitha; Bhat, Ajay N.

In: Journal of Clinical and Diagnostic Research, Vol. 12, No. 3, 01.03.2018, p. OC08-OC10.

Research output: Contribution to journalArticle

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T1 - Role of hypomagnesaemia in acute kidney injury

AU - Chintala, Ventakarakesh

AU - Prabhu, Venkataraya M.

AU - Boyanagari, Manaswitha

AU - Bhat, Ajay N.

PY - 2018/3/1

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N2 - Introduction: Acute Kidney Injury (AKI) is a common problem with various causes and consequences like electrolyte disturbances in the form of hypocalcaemia, hypokalemia, hyperkalemia depending on the phase. Serum magnesium concentration of <1.5 meq/L is defined as hypomagnesaemia and is one of the common electrolyte abnormality. Serum magnesium levels are not routinely done in AKI cases. Aim: The aim of our study was to assess the role of hypomagnesaemia as a risk factor for non recovery of AKI. Materials and Methods: A cross-sectional study was conducted between July 2014 and August 2015 with a sample of 100 patients. The decrease in magnesium <1.5 meq/L was defined as hypomagnesaemia. AKI was defined as per KDIGO criteria. Day 1, day 3 and day 6 magnesium levels were measured. Results: Prevalence of hypomagnesaemia was 69%, 43% and 27% on day 1, day 3 and day 6 respectively. It was observed that hypomagnesaemia on day 1 was significantly associated with recovery of AKI (p=0.004). Conclusion: Prevalence of hypomagnesaemia was significantly higher in AKI patients and hypomagnesaemia on day 1 was associated with recovery. However, magnesium levels on day 3 and day 6 had no significant correlation with the renal function in AKI.

AB - Introduction: Acute Kidney Injury (AKI) is a common problem with various causes and consequences like electrolyte disturbances in the form of hypocalcaemia, hypokalemia, hyperkalemia depending on the phase. Serum magnesium concentration of <1.5 meq/L is defined as hypomagnesaemia and is one of the common electrolyte abnormality. Serum magnesium levels are not routinely done in AKI cases. Aim: The aim of our study was to assess the role of hypomagnesaemia as a risk factor for non recovery of AKI. Materials and Methods: A cross-sectional study was conducted between July 2014 and August 2015 with a sample of 100 patients. The decrease in magnesium <1.5 meq/L was defined as hypomagnesaemia. AKI was defined as per KDIGO criteria. Day 1, day 3 and day 6 magnesium levels were measured. Results: Prevalence of hypomagnesaemia was 69%, 43% and 27% on day 1, day 3 and day 6 respectively. It was observed that hypomagnesaemia on day 1 was significantly associated with recovery of AKI (p=0.004). Conclusion: Prevalence of hypomagnesaemia was significantly higher in AKI patients and hypomagnesaemia on day 1 was associated with recovery. However, magnesium levels on day 3 and day 6 had no significant correlation with the renal function in AKI.

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