Role of Rapid Tetanus Antibody Test in Accident and Emergency Department

A. Chithra, K. M. Cariappa, Abhay Taranath Kamath, Adarsh Kudva

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Introduction: Tetanus remains a problem of immense concern worldwide. Management of tetanus with its attendant complications are challenges to the physician and its prevention is the chief priority. The choice of tetanus prophylaxis for patients with wounds depends on obtaining their vaccination history, which has been demonstrated to be unreliable. The tetanus antibody test may avoid inadequate prophylactic measures and reduce costs. Purpose: This study is conducted to determine the feasibility of rapid tetanus antibody test (SD Bioline) in the accident and emergency department. Methods: A randomized prospective study was conducted on 50 patients, divided into two groups—A and B with 25 patients each respectively. Group A had patients with a history of tetanus immunization <5 years elapsed from the last booster dose. Group B had patients who did not know the immunization status or more than 5 years elapsed from the last booster dose of tetanus immunization. Groups A and B were further classified into Group 1 and Group 2 based on whether the wound is tetanus prone or a clean wound respectively. Tetanus antibody test was done using whole-blood from the patients by finger prick. Results: Among the 50 patients, 25 (50 %) were classified as ‘unprotected’ according to the history. Thirteen of the 25 patients showed tetanus antibody positive. In Group A, only 9 of the 25 patients showed tetanus antibody positive. Conclusion: The rapid tetanus antibody test in the emergency room could make tetanus prevention more accurate with improved technical feasibility. The test may eliminate unnecessary injecting of vaccine, reduce the cost and can be performed at the hospital setting.

Original languageEnglish
Pages (from-to)784-788
Number of pages5
JournalJournal of Maxillofacial and Oral Surgery
Volume14
Issue number3
DOIs
Publication statusPublished - 01-09-2015

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Tetanus
Hospital Emergency Service
Antibodies
Immunization
Wounds and Injuries
History
Costs and Cost Analysis
Fingers
Vaccination
Vaccines

All Science Journal Classification (ASJC) codes

  • Oral Surgery
  • Surgery
  • Otorhinolaryngology

Cite this

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abstract = "Introduction: Tetanus remains a problem of immense concern worldwide. Management of tetanus with its attendant complications are challenges to the physician and its prevention is the chief priority. The choice of tetanus prophylaxis for patients with wounds depends on obtaining their vaccination history, which has been demonstrated to be unreliable. The tetanus antibody test may avoid inadequate prophylactic measures and reduce costs. Purpose: This study is conducted to determine the feasibility of rapid tetanus antibody test (SD Bioline) in the accident and emergency department. Methods: A randomized prospective study was conducted on 50 patients, divided into two groups—A and B with 25 patients each respectively. Group A had patients with a history of tetanus immunization <5 years elapsed from the last booster dose. Group B had patients who did not know the immunization status or more than 5 years elapsed from the last booster dose of tetanus immunization. Groups A and B were further classified into Group 1 and Group 2 based on whether the wound is tetanus prone or a clean wound respectively. Tetanus antibody test was done using whole-blood from the patients by finger prick. Results: Among the 50 patients, 25 (50 {\%}) were classified as ‘unprotected’ according to the history. Thirteen of the 25 patients showed tetanus antibody positive. In Group A, only 9 of the 25 patients showed tetanus antibody positive. Conclusion: The rapid tetanus antibody test in the emergency room could make tetanus prevention more accurate with improved technical feasibility. The test may eliminate unnecessary injecting of vaccine, reduce the cost and can be performed at the hospital setting.",
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Role of Rapid Tetanus Antibody Test in Accident and Emergency Department. / Chithra, A.; Cariappa, K. M.; Kamath, Abhay Taranath; Kudva, Adarsh.

In: Journal of Maxillofacial and Oral Surgery, Vol. 14, No. 3, 01.09.2015, p. 784-788.

Research output: Contribution to journalArticle

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