9 Citations (Scopus)

Abstract

Aims: To evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects. Methods: We conducted a cross-sectional study among 30 freshly diagnosed subjects of diabetes mellitus and 30 volunteers with no diabetes mellitus. Serum and salivary MDS levels were evaluated among all the subjects. Results: The mean serum MDA in group controls and diabetics was 0.95 ± 0.13 and 3.11 ± 0.42. The mean salivary MDA in group controls and diabetics was 0.26 ± 0.05 μmol/l and 0.81 ± 0.07 μmol/l. The mean serum and salivary MDA levels were significantly higher in group diabetics than control group (p < 0.001 and <0.001) respectively. There was significant positive strong correlation between serum and salivary MDA levels in both controls and diabetics groups (r = 0.857, p < 0.001 and r = 0.891, p < 0.001) respectively. Conclusion: MDA was detectable in saliva in both diabetic and control groups. There was a positive significant correlation between salivary and serum MDA in diabetic and control subjects. Hence, salivary MDA appears to be an indicator of serum MDA concentration.

Original languageEnglish
Pages (from-to)42-45
Number of pages4
JournalJournal of Oral Biology and Craniofacial Research
Volume6
Issue number1
DOIs
Publication statusPublished - 01-01-2016

Fingerprint

Malondialdehyde
Oxidative Stress
Control Groups
Serum
Diabetes Mellitus
Saliva
Type 2 Diabetes Mellitus
Volunteers
Cross-Sectional Studies

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Dentistry(all)

Cite this

@article{e0c6f6cdcefa43f29fab1968aad9ef44,
title = "Role of salivary malondialdehyde in assessment of oxidative stress among diabetics",
abstract = "Aims: To evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects. Methods: We conducted a cross-sectional study among 30 freshly diagnosed subjects of diabetes mellitus and 30 volunteers with no diabetes mellitus. Serum and salivary MDS levels were evaluated among all the subjects. Results: The mean serum MDA in group controls and diabetics was 0.95 ± 0.13 and 3.11 ± 0.42. The mean salivary MDA in group controls and diabetics was 0.26 ± 0.05 μmol/l and 0.81 ± 0.07 μmol/l. The mean serum and salivary MDA levels were significantly higher in group diabetics than control group (p < 0.001 and <0.001) respectively. There was significant positive strong correlation between serum and salivary MDA levels in both controls and diabetics groups (r = 0.857, p < 0.001 and r = 0.891, p < 0.001) respectively. Conclusion: MDA was detectable in saliva in both diabetic and control groups. There was a positive significant correlation between salivary and serum MDA in diabetic and control subjects. Hence, salivary MDA appears to be an indicator of serum MDA concentration.",
author = "Komal Smriti and Pai, {Keerthilatha Muralidhar} and Vineetha Ravindranath and Pentapati, {Kalyana Chakravarthy}",
year = "2016",
month = "1",
day = "1",
doi = "10.1016/j.jobcr.2015.12.004",
language = "English",
volume = "6",
pages = "42--45",
journal = "Journal of Oral Biology and Craniofacial Research",
issn = "2212-4268",
publisher = "Elsevier BV",
number = "1",

}

TY - JOUR

T1 - Role of salivary malondialdehyde in assessment of oxidative stress among diabetics

AU - Smriti, Komal

AU - Pai, Keerthilatha Muralidhar

AU - Ravindranath, Vineetha

AU - Pentapati, Kalyana Chakravarthy

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Aims: To evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects. Methods: We conducted a cross-sectional study among 30 freshly diagnosed subjects of diabetes mellitus and 30 volunteers with no diabetes mellitus. Serum and salivary MDS levels were evaluated among all the subjects. Results: The mean serum MDA in group controls and diabetics was 0.95 ± 0.13 and 3.11 ± 0.42. The mean salivary MDA in group controls and diabetics was 0.26 ± 0.05 μmol/l and 0.81 ± 0.07 μmol/l. The mean serum and salivary MDA levels were significantly higher in group diabetics than control group (p < 0.001 and <0.001) respectively. There was significant positive strong correlation between serum and salivary MDA levels in both controls and diabetics groups (r = 0.857, p < 0.001 and r = 0.891, p < 0.001) respectively. Conclusion: MDA was detectable in saliva in both diabetic and control groups. There was a positive significant correlation between salivary and serum MDA in diabetic and control subjects. Hence, salivary MDA appears to be an indicator of serum MDA concentration.

AB - Aims: To evaluate and compare the salivary content of malondialdehyde (MDA) in patients with type 2 diabetes and control subjects. Methods: We conducted a cross-sectional study among 30 freshly diagnosed subjects of diabetes mellitus and 30 volunteers with no diabetes mellitus. Serum and salivary MDS levels were evaluated among all the subjects. Results: The mean serum MDA in group controls and diabetics was 0.95 ± 0.13 and 3.11 ± 0.42. The mean salivary MDA in group controls and diabetics was 0.26 ± 0.05 μmol/l and 0.81 ± 0.07 μmol/l. The mean serum and salivary MDA levels were significantly higher in group diabetics than control group (p < 0.001 and <0.001) respectively. There was significant positive strong correlation between serum and salivary MDA levels in both controls and diabetics groups (r = 0.857, p < 0.001 and r = 0.891, p < 0.001) respectively. Conclusion: MDA was detectable in saliva in both diabetic and control groups. There was a positive significant correlation between salivary and serum MDA in diabetic and control subjects. Hence, salivary MDA appears to be an indicator of serum MDA concentration.

UR - http://www.scopus.com/inward/record.url?scp=84969220077&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84969220077&partnerID=8YFLogxK

U2 - 10.1016/j.jobcr.2015.12.004

DO - 10.1016/j.jobcr.2015.12.004

M3 - Article

AN - SCOPUS:84969220077

VL - 6

SP - 42

EP - 45

JO - Journal of Oral Biology and Craniofacial Research

JF - Journal of Oral Biology and Craniofacial Research

SN - 2212-4268

IS - 1

ER -