Role of UHRF1 in malignancy and its function as a therapeutic target for molecular docking towards the SRA domain

Sravani Polepalli, Sophia M. George, R. Valli Sri Vidya, Gabriel Sunil Rodrigues, L. Ramachandra, Raghu Chandrashekar, Deepak Nayak M, Praveen P.N. Rao, Richard G. Pestell, Mahadev Rao

Research output: Contribution to journalReview article

Abstract

The figure describes the location of UHRF1 (Ubiquitin-like with containing PHD and RING Finger domains 1) gene, mRNA and protein synthesis in the tumor cell and its structural domains with a focus on the docking of Naphthazarin on the SRA domain of UHRF1, resulting in reduction of tumor size.

Original languageEnglish
Article number105558
JournalInternational Journal of Biochemistry and Cell Biology
Volume114
DOIs
Publication statusPublished - 01-09-2019

Fingerprint

Tumors
RING Finger Domains
Ubiquitin
Neoplasms
Genes
Cells
Messenger RNA
Therapeutics
Proteins
naphthazarin

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Cell Biology

Cite this

Polepalli, Sravani ; George, Sophia M. ; Valli Sri Vidya, R. ; Rodrigues, Gabriel Sunil ; Ramachandra, L. ; Chandrashekar, Raghu ; M, Deepak Nayak ; Rao, Praveen P.N. ; Pestell, Richard G. ; Rao, Mahadev. / Role of UHRF1 in malignancy and its function as a therapeutic target for molecular docking towards the SRA domain. In: International Journal of Biochemistry and Cell Biology. 2019 ; Vol. 114.
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Role of UHRF1 in malignancy and its function as a therapeutic target for molecular docking towards the SRA domain. / Polepalli, Sravani; George, Sophia M.; Valli Sri Vidya, R.; Rodrigues, Gabriel Sunil; Ramachandra, L.; Chandrashekar, Raghu; M, Deepak Nayak; Rao, Praveen P.N.; Pestell, Richard G.; Rao, Mahadev.

In: International Journal of Biochemistry and Cell Biology, Vol. 114, 105558, 01.09.2019.

Research output: Contribution to journalReview article

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AU - Polepalli, Sravani

AU - George, Sophia M.

AU - Valli Sri Vidya, R.

AU - Rodrigues, Gabriel Sunil

AU - Ramachandra, L.

AU - Chandrashekar, Raghu

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AU - Rao, Praveen P.N.

AU - Pestell, Richard G.

AU - Rao, Mahadev

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