Role of UHRF1 in malignancy and its function as a therapeutic target for molecular docking towards the SRA domain

Sravani Polepalli, Sophia M. George, R. Valli Sri Vidya, Gabriel Sunil Rodrigues, L. Ramachandra, Raghu Chandrashekar, Deepak Nayak M, Praveen P.N. Rao, Richard G. Pestell, Mahadev Rao

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

The figure describes the location of UHRF1 (Ubiquitin-like with containing PHD and RING Finger domains 1) gene, mRNA and protein synthesis in the tumor cell and its structural domains with a focus on the docking of Naphthazarin on the SRA domain of UHRF1, resulting in reduction of tumor size.

Original languageEnglish
Article number105558
JournalInternational Journal of Biochemistry and Cell Biology
Volume114
DOIs
Publication statusPublished - 01-09-2019

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Cell Biology

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