Sacrococcygeal myxopapillary ependymoma with anaplastic ependymoma component in an infant

Shrijeet Chakraborti, Hema Kini, K. Ganesh Pai, Vidya Upadhyaya

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Sacrococcygeal location of myxopapillary ependymoma (MPE) is uncommon. Local recurrence and metastases are on record inspite of its benign characteristics. We report a rare case of sacrococcygeal MPE in an 11-month-old female child who showed typical myxopapillary ependymal histology along with anaplastic ependymal component. Ki-67 labeling index in the myxopapillary component was 4-5% and in the anaplastic component was 70%. Six weeks after gross total resection of the tumor, the child presented with local recurrence and metastasis in the right inguinal lymph nodes and was treated with chemotherapy. The present case of sacrococcygeal MPE with anaplastic ependymoma component is the second case on record in the medical literature, and the first case without any syndromic features. Metastasis in this case can be explained because of the anaplastic component, with mitotic count of 5-6/high power field and high Ki-67 labeling index.

Original languageEnglish
Pages (from-to)218-220
Number of pages3
JournalJournal of Pediatric Neurosciences
Volume7
Issue number3
DOIs
Publication statusPublished - 01-09-2012

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Ependymoma
Neoplasm Metastasis
Recurrence
Groin
Medical Records
Histology
Lymph Nodes
Drug Therapy
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Neuroscience(all)

Cite this

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abstract = "Sacrococcygeal location of myxopapillary ependymoma (MPE) is uncommon. Local recurrence and metastases are on record inspite of its benign characteristics. We report a rare case of sacrococcygeal MPE in an 11-month-old female child who showed typical myxopapillary ependymal histology along with anaplastic ependymal component. Ki-67 labeling index in the myxopapillary component was 4-5{\%} and in the anaplastic component was 70{\%}. Six weeks after gross total resection of the tumor, the child presented with local recurrence and metastasis in the right inguinal lymph nodes and was treated with chemotherapy. The present case of sacrococcygeal MPE with anaplastic ependymoma component is the second case on record in the medical literature, and the first case without any syndromic features. Metastasis in this case can be explained because of the anaplastic component, with mitotic count of 5-6/high power field and high Ki-67 labeling index.",
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Sacrococcygeal myxopapillary ependymoma with anaplastic ependymoma component in an infant. / Chakraborti, Shrijeet; Kini, Hema; Pai, K. Ganesh; Upadhyaya, Vidya.

In: Journal of Pediatric Neurosciences, Vol. 7, No. 3, 01.09.2012, p. 218-220.

Research output: Contribution to journalArticle

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