Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix

Sharmila Upadhya, Subramanya Upadhya, K. S. Prabhu

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.

Original languageEnglish
Pages (from-to)20-24
Number of pages5
JournalIndian Journal of Clinical Biochemistry
Volume17
Issue number1
DOIs
Publication statusPublished - 01-01-2002
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

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