Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix

Sharmila Upadhya; Subramanya Upadhya; K. S. Prabhu

doi:10.1007/BF02867936

Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix

Sharmila Upadhya, Subramanya Upadhya, K. S. Prabhu

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.

Original language	English
Pages (from-to)	20-24
Number of pages	5
Journal	Indian Journal of Clinical Biochemistry
Volume	17
Issue number	1
DOIs	https://doi.org/10.1007/BF02867936
Publication status	Published - 01-01-2002
Externally published	Yes

All Science Journal Classification (ASJC) codes

Clinical Biochemistry

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10.1007/BF02867936

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