Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix

Sharmila Upadhya, Subramanya Upadhya, K. S. Prabhu

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.

Original languageEnglish
Pages (from-to)20-24
Number of pages5
JournalIndian Journal of Clinical Biochemistry
Volume17
Issue number1
DOIs
Publication statusPublished - 01-01-2002
Externally publishedYes

Fingerprint

Ceruloplasmin
Glycoconjugates
Uterine Cervical Neoplasms
Hexoses
Fucose
N-Acetylneuraminic Acid
Serum
Hexosamines
Acute-Phase Proteins
Neoplasms

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

Upadhya, Sharmila ; Upadhya, Subramanya ; Prabhu, K. S. / Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix. In: Indian Journal of Clinical Biochemistry. 2002 ; Vol. 17, No. 1. pp. 20-24.
@article{a65207ba576941a884ff330308fb7c82,
title = "Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix",
abstract = "The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.",
author = "Sharmila Upadhya and Subramanya Upadhya and Prabhu, {K. S.}",
year = "2002",
month = "1",
day = "1",
doi = "10.1007/BF02867936",
language = "English",
volume = "17",
pages = "20--24",
journal = "Indian Journal of Clinical Biochemistry",
issn = "0970-1915",
publisher = "Springer India",
number = "1",

}

Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix. / Upadhya, Sharmila; Upadhya, Subramanya; Prabhu, K. S.

In: Indian Journal of Clinical Biochemistry, Vol. 17, No. 1, 01.01.2002, p. 20-24.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix

AU - Upadhya, Sharmila

AU - Upadhya, Subramanya

AU - Prabhu, K. S.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.

AB - The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.

UR - http://www.scopus.com/inward/record.url?scp=33645492015&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645492015&partnerID=8YFLogxK

U2 - 10.1007/BF02867936

DO - 10.1007/BF02867936

M3 - Article

VL - 17

SP - 20

EP - 24

JO - Indian Journal of Clinical Biochemistry

JF - Indian Journal of Clinical Biochemistry

SN - 0970-1915

IS - 1

ER -