Abstract
The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.
| Original language | English |
|---|---|
| Pages (from-to) | 20-24 |
| Number of pages | 5 |
| Journal | Indian Journal of Clinical Biochemistry |
| Volume | 17 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 01-01-2002 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Clinical Biochemistry
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Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix. / Upadhya, Sharmila; Upadhya, Subramanya; Prabhu, K. S.
In: Indian Journal of Clinical Biochemistry, Vol. 17, No. 1, 01.01.2002, p. 20-24.Research output: Contribution to journal › Article
TY - JOUR
T1 - Serum glycoconjugates and ceruloplasmin in cancer of uterine cervix
AU - Upadhya, Sharmila
AU - Upadhya, Subramanya
AU - Prabhu, K. S.
PY - 2002/1/1
Y1 - 2002/1/1
N2 - The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.
AB - The present study was done to assess the levels of glycoconjugates and ceruloplasmin in sera of patients with cervical cancer. Serum hexoses, hexosamines, sialic acid and fucose are elevated in a variety of inflammatory and neoplastic conditions. All the glycoconjugates, except fucose were increased in serum of patients compared to controls. Also, hexoses and sialic acid levels were high in patients with later stages of cancer compared to patients with early stage disease (P=<0.0001,P=0.03). Serum ceruloplasmin was increased in patients with early stage cancer (51.5mg/dl) and with late stage cancer (61mg/dl) compared to controls (38mg/dl). The elevated glycoconjugates may be the result of inflammatory reaction associated with neoplasia, as serum ceruloplasmin (an acute phase reactant) is also increased in these patients.
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UR - http://www.scopus.com/inward/citedby.url?scp=33645492015&partnerID=8YFLogxK
U2 - 10.1007/BF02867936
DO - 10.1007/BF02867936
M3 - Article
VL - 17
SP - 20
EP - 24
JO - Indian Journal of Clinical Biochemistry
JF - Indian Journal of Clinical Biochemistry
SN - 0970-1915
IS - 1
ER -