Serum Lactate Dehydrogenase in Non-Hodgkin’s Lymphoma

A Prognostic Indicator

Charu Yadav, Afzal Ahmad, Benedicta D’Souza, Ashish Agarwal, M. Nandini, K. Ashok Prabhu, Vivian D’Souza

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Non-Hodgkin’s lymphoma constitutes a group of disorders originating from the malignant transformation of lymphocytes and involving either the lymph nodes or extranodal sites. NHL commonly presents in the sixth to seventh decade of life with a male preponderance (50–75 %). Recent studies have shown importance of serum LDH in prognosis of NHL. Authors report a case of a 63 year old male presenting with complaints of fever and backache for past 4 months. General and systemic examination revealed bilateral axillary lymphadenopathy and splenomegaly respectively. Serum LDH level was highly elevated (3441 U/l). Excisional axillary and bone marrow biopsy were done before oncology referral. Complete workup revealed diffuse Non-Hodgkin’s lymphoma with bone marrow infiltration. Patient died because of acute renal failure due to NHL and DM 2 (Type 2 diabetes mellitus).

Original languageEnglish
Pages (from-to)240-242
Number of pages3
JournalIndian Journal of Clinical Biochemistry
Volume31
Issue number2
DOIs
Publication statusPublished - 01-04-2016

Fingerprint

L-Lactate Dehydrogenase
Non-Hodgkin's Lymphoma
Bone
Oncology
Lymphocytes
Biopsy
Medical problems
Bone Marrow
Serum
Infiltration
Splenomegaly
Back Pain
Lymphocyte Activation
Acute Kidney Injury
Type 2 Diabetes Mellitus
Fever
Referral and Consultation
Lymph Nodes

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

Yadav, Charu ; Ahmad, Afzal ; D’Souza, Benedicta ; Agarwal, Ashish ; Nandini, M. ; Ashok Prabhu, K. ; D’Souza, Vivian. / Serum Lactate Dehydrogenase in Non-Hodgkin’s Lymphoma : A Prognostic Indicator. In: Indian Journal of Clinical Biochemistry. 2016 ; Vol. 31, No. 2. pp. 240-242.
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Yadav, C, Ahmad, A, D’Souza, B, Agarwal, A, Nandini, M, Ashok Prabhu, K & D’Souza, V 2016, 'Serum Lactate Dehydrogenase in Non-Hodgkin’s Lymphoma: A Prognostic Indicator', Indian Journal of Clinical Biochemistry, vol. 31, no. 2, pp. 240-242. https://doi.org/10.1007/s12291-015-0511-3

Serum Lactate Dehydrogenase in Non-Hodgkin’s Lymphoma : A Prognostic Indicator. / Yadav, Charu; Ahmad, Afzal; D’Souza, Benedicta; Agarwal, Ashish; Nandini, M.; Ashok Prabhu, K.; D’Souza, Vivian.

In: Indian Journal of Clinical Biochemistry, Vol. 31, No. 2, 01.04.2016, p. 240-242.

Research output: Contribution to journalArticle

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T2 - A Prognostic Indicator

AU - Yadav, Charu

AU - Ahmad, Afzal

AU - D’Souza, Benedicta

AU - Agarwal, Ashish

AU - Nandini, M.

AU - Ashok Prabhu, K.

AU - D’Souza, Vivian

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AB - Non-Hodgkin’s lymphoma constitutes a group of disorders originating from the malignant transformation of lymphocytes and involving either the lymph nodes or extranodal sites. NHL commonly presents in the sixth to seventh decade of life with a male preponderance (50–75 %). Recent studies have shown importance of serum LDH in prognosis of NHL. Authors report a case of a 63 year old male presenting with complaints of fever and backache for past 4 months. General and systemic examination revealed bilateral axillary lymphadenopathy and splenomegaly respectively. Serum LDH level was highly elevated (3441 U/l). Excisional axillary and bone marrow biopsy were done before oncology referral. Complete workup revealed diffuse Non-Hodgkin’s lymphoma with bone marrow infiltration. Patient died because of acute renal failure due to NHL and DM 2 (Type 2 diabetes mellitus).

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