TY - JOUR
T1 - Serum uric acid levels in Type 2 diabetes mellitus
T2 - Is there a linear relationship with severity of carotid atherosclerosis?
AU - Venishetty, Shantan
AU - Bhat, Rama
AU - Rajagopal, K. V.
N1 - Publisher Copyright:
© 2018 Indian Journal of Endocrinology and Metabolism Published by Wolters Kluwer - Medknow.
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Aims: The aim of this study was to correlate serum uric acid (SUA) levels and carotid intima-media thickness (CIMT) in patients with type 2 diabetes mellitus (DM). Settings and Design: This study was a cross-sectional observational study on 103 diabetic patients conducted from September 2015 to May 2017. Subjects and Methods: We screened 103 patients with type 2 DM between the ages of 30-65 years. SUA levels and the CIMT were measured. The patients were divided into quartiles based on uric acid level. The CIMT of the quartiles is compared and analyzed. Statistical Analysis Used: Chi-squared test, Analysis of Variance, and Pearson's correlation. Results: Uric acid levels were positively associated with CIMT (P = 0.001). The association remained significant after further adjustment for potential confounders. Strong correlation was found among them as depicted by correlation coefficient (r = 0.779). Conclusions: Carotid atherosclerosis as measured by IMT is associated with SUA levels in patients with type 2 DM.
AB - Aims: The aim of this study was to correlate serum uric acid (SUA) levels and carotid intima-media thickness (CIMT) in patients with type 2 diabetes mellitus (DM). Settings and Design: This study was a cross-sectional observational study on 103 diabetic patients conducted from September 2015 to May 2017. Subjects and Methods: We screened 103 patients with type 2 DM between the ages of 30-65 years. SUA levels and the CIMT were measured. The patients were divided into quartiles based on uric acid level. The CIMT of the quartiles is compared and analyzed. Statistical Analysis Used: Chi-squared test, Analysis of Variance, and Pearson's correlation. Results: Uric acid levels were positively associated with CIMT (P = 0.001). The association remained significant after further adjustment for potential confounders. Strong correlation was found among them as depicted by correlation coefficient (r = 0.779). Conclusions: Carotid atherosclerosis as measured by IMT is associated with SUA levels in patients with type 2 DM.
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U2 - 10.4103/ijem.IJEM_641_17
DO - 10.4103/ijem.IJEM_641_17
M3 - Article
AN - SCOPUS:85053759461
SN - 2230-8210
VL - 22
SP - 678
EP - 682
JO - Indian Journal of Endocrinology and Metabolism
JF - Indian Journal of Endocrinology and Metabolism
IS - 5
ER -
