Severity of coronary artery disease in type 2 diabetes mellitus: Does the timing matter?

Mukund P. Srinivasan, Padmanabh K. Kamath, Narayan M. Bhat, Narasimha D. Pai, Rajesh U. Bhat, Tejas D. Shah, Anish Singhal, Chakrapani Mahabala

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Abstract

Aim The aim of our study was to compare the angiographic changes in 53 nondiabetic patients, 54 type 2 diabetic patients of less than 5 years of duration, 41 patients with 5-10 years of diabetes, and 27 with more than 10 years of diabetic duration. Methods In this cross-sectional study, 175 patients, who underwent coronary angiogram for the evaluation of the coronary artery disease (CAD), were recruited. Based on the angiographic findings, syntax score, vessel score, and coronary collaterals grading were analyzed. The biochemical analysis was done by using the auto analyzer. Results A significant increase in the mean syntax score (p = 0.019), vessel score (p = 0.007), and coronary collateral grade (p = 0.008) was observed in the patients with 5-10 years of diabetes when compared to those with less than 5 years of diabetic duration. There was no significant difference in the mean syntax score (p = 0.979), vessel score (p = 0.299), and collateral grade (p = 0.842) between the patients with 5-10 years and more than 10 years of diabetes. The difference in the mean syntax score (p = 0.791), vessel score (p = 0.098), and collateral grade (p = 0.661) between the nondiabetic and the patients with less than 5 years of diabetes was not significant. Conclusion A significant structural change in the coronary arteries was found among the patients with 5-10 years of diabetes.

Original languageEnglish
Pages (from-to)158-163
Number of pages6
JournalIndian Heart Journal
Volume68
Issue number2
DOIs
Publication statusPublished - 01-03-2016

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Type 2 Diabetes Mellitus
Coronary Artery Disease
Coronary Vessels
Angiography
Cross-Sectional Studies

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Severity of coronary artery disease in type 2 diabetes mellitus: Does the timing matter?",
abstract = "Aim The aim of our study was to compare the angiographic changes in 53 nondiabetic patients, 54 type 2 diabetic patients of less than 5 years of duration, 41 patients with 5-10 years of diabetes, and 27 with more than 10 years of diabetic duration. Methods In this cross-sectional study, 175 patients, who underwent coronary angiogram for the evaluation of the coronary artery disease (CAD), were recruited. Based on the angiographic findings, syntax score, vessel score, and coronary collaterals grading were analyzed. The biochemical analysis was done by using the auto analyzer. Results A significant increase in the mean syntax score (p = 0.019), vessel score (p = 0.007), and coronary collateral grade (p = 0.008) was observed in the patients with 5-10 years of diabetes when compared to those with less than 5 years of diabetic duration. There was no significant difference in the mean syntax score (p = 0.979), vessel score (p = 0.299), and collateral grade (p = 0.842) between the patients with 5-10 years and more than 10 years of diabetes. The difference in the mean syntax score (p = 0.791), vessel score (p = 0.098), and collateral grade (p = 0.661) between the nondiabetic and the patients with less than 5 years of diabetes was not significant. Conclusion A significant structural change in the coronary arteries was found among the patients with 5-10 years of diabetes.",
author = "Srinivasan, {Mukund P.} and Kamath, {Padmanabh K.} and Bhat, {Narayan M.} and Pai, {Narasimha D.} and Bhat, {Rajesh U.} and Shah, {Tejas D.} and Anish Singhal and Chakrapani Mahabala",
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Severity of coronary artery disease in type 2 diabetes mellitus : Does the timing matter? / Srinivasan, Mukund P.; Kamath, Padmanabh K.; Bhat, Narayan M.; Pai, Narasimha D.; Bhat, Rajesh U.; Shah, Tejas D.; Singhal, Anish; Mahabala, Chakrapani.

In: Indian Heart Journal, Vol. 68, No. 2, 01.03.2016, p. 158-163.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Severity of coronary artery disease in type 2 diabetes mellitus

T2 - Does the timing matter?

AU - Srinivasan, Mukund P.

AU - Kamath, Padmanabh K.

AU - Bhat, Narayan M.

AU - Pai, Narasimha D.

AU - Bhat, Rajesh U.

AU - Shah, Tejas D.

AU - Singhal, Anish

AU - Mahabala, Chakrapani

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Aim The aim of our study was to compare the angiographic changes in 53 nondiabetic patients, 54 type 2 diabetic patients of less than 5 years of duration, 41 patients with 5-10 years of diabetes, and 27 with more than 10 years of diabetic duration. Methods In this cross-sectional study, 175 patients, who underwent coronary angiogram for the evaluation of the coronary artery disease (CAD), were recruited. Based on the angiographic findings, syntax score, vessel score, and coronary collaterals grading were analyzed. The biochemical analysis was done by using the auto analyzer. Results A significant increase in the mean syntax score (p = 0.019), vessel score (p = 0.007), and coronary collateral grade (p = 0.008) was observed in the patients with 5-10 years of diabetes when compared to those with less than 5 years of diabetic duration. There was no significant difference in the mean syntax score (p = 0.979), vessel score (p = 0.299), and collateral grade (p = 0.842) between the patients with 5-10 years and more than 10 years of diabetes. The difference in the mean syntax score (p = 0.791), vessel score (p = 0.098), and collateral grade (p = 0.661) between the nondiabetic and the patients with less than 5 years of diabetes was not significant. Conclusion A significant structural change in the coronary arteries was found among the patients with 5-10 years of diabetes.

AB - Aim The aim of our study was to compare the angiographic changes in 53 nondiabetic patients, 54 type 2 diabetic patients of less than 5 years of duration, 41 patients with 5-10 years of diabetes, and 27 with more than 10 years of diabetic duration. Methods In this cross-sectional study, 175 patients, who underwent coronary angiogram for the evaluation of the coronary artery disease (CAD), were recruited. Based on the angiographic findings, syntax score, vessel score, and coronary collaterals grading were analyzed. The biochemical analysis was done by using the auto analyzer. Results A significant increase in the mean syntax score (p = 0.019), vessel score (p = 0.007), and coronary collateral grade (p = 0.008) was observed in the patients with 5-10 years of diabetes when compared to those with less than 5 years of diabetic duration. There was no significant difference in the mean syntax score (p = 0.979), vessel score (p = 0.299), and collateral grade (p = 0.842) between the patients with 5-10 years and more than 10 years of diabetes. The difference in the mean syntax score (p = 0.791), vessel score (p = 0.098), and collateral grade (p = 0.661) between the nondiabetic and the patients with less than 5 years of diabetes was not significant. Conclusion A significant structural change in the coronary arteries was found among the patients with 5-10 years of diabetes.

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SN - 0019-4832

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