Significance of foetal transcerebellar diameter in foetal biometry

A pilot study

Ramireddy Harikiran Reddy, Kumar Prashanth, Mahale Ajit

Research output: Contribution to journalArticle

Abstract

Introduction: The most important parameter needed for appropriate management of pregnant women is accurate Gestational Age (GA). Routine sonographic estimation of GA by using Biparietal Diameter (BPD), Femur Length (FL), Abdominal Circumference (AC) and Head Circumference (HC) assumed important role in management of pregnancy. However, these parameters have limitations. BPD and HC are not reliable in case of moulding of foetal head in third trimester. Similarly, femur length is shortened in cases of achondroplasia. Transcerebellar Diameter (TCD) was developed as an alternative parameter of foetal brain growth and for estimation of GA. Aim: To evaluate accuracy of predicting GA using Foetal Transcerebellar Diameter (TCD) and to compare between TCD and other existing parameters in evaluating GA in 15 to 40 weeks of gestation. Materials and Methods: A prospective study was carried out in 100 pregnant women between 15 to 40 weeks of gestation, who came for routine antenatal sonography. Transcerebellar diameter was measured along with routine parameters. Subjects were divided into two groups based on GA (15-28 and 29-40 weeks). Gestational age using TCD and other parameters was calculated and compared with gestational age based on Last Menstrual Period (LMP). Correlation between the GA by LMP with GA by other ultrasound parameters was done by using Karl Pearson’s Correlation(r). Results: In 15-28 weeks, all parameters had nearly equal r-values. Among all parameters, TCD revealed highest correlation with value of 0.997. In 29-40 weeks, there was considerable difference in r-values. An r-value of 0.982 was noted, when the GA by TCD and LMP was compared, r-value of which is more than the other parameters. The least correlation was seen with BPD, r=0.951. The second most accurate correlation was seen with the FL with r-value of 0.981. Conclusion: TCD is an accurate parameter in estimation of gestational age in second and third trimesters as its values are in close relation with that of GA by LMP. It is also better predictor of the gestational age when compared to other parameters especially in third trimester.

Original languageEnglish
Pages (from-to)TC01-TC04
JournalJournal of Clinical and Diagnostic Research
Volume11
Issue number6
DOIs
Publication statusPublished - 01-06-2017
Externally publishedYes

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Biometry
Gestational Age
Ultrasonography
Molding
Brain
Ultrasonics
Third Pregnancy Trimester
Femur
Head
Pregnancy
Pregnant Women
Achondroplasia
Second Pregnancy Trimester
Fetal Development

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

Reddy, Ramireddy Harikiran ; Prashanth, Kumar ; Ajit, Mahale. / Significance of foetal transcerebellar diameter in foetal biometry : A pilot study. In: Journal of Clinical and Diagnostic Research. 2017 ; Vol. 11, No. 6. pp. TC01-TC04.
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abstract = "Introduction: The most important parameter needed for appropriate management of pregnant women is accurate Gestational Age (GA). Routine sonographic estimation of GA by using Biparietal Diameter (BPD), Femur Length (FL), Abdominal Circumference (AC) and Head Circumference (HC) assumed important role in management of pregnancy. However, these parameters have limitations. BPD and HC are not reliable in case of moulding of foetal head in third trimester. Similarly, femur length is shortened in cases of achondroplasia. Transcerebellar Diameter (TCD) was developed as an alternative parameter of foetal brain growth and for estimation of GA. Aim: To evaluate accuracy of predicting GA using Foetal Transcerebellar Diameter (TCD) and to compare between TCD and other existing parameters in evaluating GA in 15 to 40 weeks of gestation. Materials and Methods: A prospective study was carried out in 100 pregnant women between 15 to 40 weeks of gestation, who came for routine antenatal sonography. Transcerebellar diameter was measured along with routine parameters. Subjects were divided into two groups based on GA (15-28 and 29-40 weeks). Gestational age using TCD and other parameters was calculated and compared with gestational age based on Last Menstrual Period (LMP). Correlation between the GA by LMP with GA by other ultrasound parameters was done by using Karl Pearson’s Correlation(r). Results: In 15-28 weeks, all parameters had nearly equal r-values. Among all parameters, TCD revealed highest correlation with value of 0.997. In 29-40 weeks, there was considerable difference in r-values. An r-value of 0.982 was noted, when the GA by TCD and LMP was compared, r-value of which is more than the other parameters. The least correlation was seen with BPD, r=0.951. The second most accurate correlation was seen with the FL with r-value of 0.981. Conclusion: TCD is an accurate parameter in estimation of gestational age in second and third trimesters as its values are in close relation with that of GA by LMP. It is also better predictor of the gestational age when compared to other parameters especially in third trimester.",
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Significance of foetal transcerebellar diameter in foetal biometry : A pilot study. / Reddy, Ramireddy Harikiran; Prashanth, Kumar; Ajit, Mahale.

In: Journal of Clinical and Diagnostic Research, Vol. 11, No. 6, 01.06.2017, p. TC01-TC04.

Research output: Contribution to journalArticle

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T1 - Significance of foetal transcerebellar diameter in foetal biometry

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AU - Reddy, Ramireddy Harikiran

AU - Prashanth, Kumar

AU - Ajit, Mahale

PY - 2017/6/1

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N2 - Introduction: The most important parameter needed for appropriate management of pregnant women is accurate Gestational Age (GA). Routine sonographic estimation of GA by using Biparietal Diameter (BPD), Femur Length (FL), Abdominal Circumference (AC) and Head Circumference (HC) assumed important role in management of pregnancy. However, these parameters have limitations. BPD and HC are not reliable in case of moulding of foetal head in third trimester. Similarly, femur length is shortened in cases of achondroplasia. Transcerebellar Diameter (TCD) was developed as an alternative parameter of foetal brain growth and for estimation of GA. Aim: To evaluate accuracy of predicting GA using Foetal Transcerebellar Diameter (TCD) and to compare between TCD and other existing parameters in evaluating GA in 15 to 40 weeks of gestation. Materials and Methods: A prospective study was carried out in 100 pregnant women between 15 to 40 weeks of gestation, who came for routine antenatal sonography. Transcerebellar diameter was measured along with routine parameters. Subjects were divided into two groups based on GA (15-28 and 29-40 weeks). Gestational age using TCD and other parameters was calculated and compared with gestational age based on Last Menstrual Period (LMP). Correlation between the GA by LMP with GA by other ultrasound parameters was done by using Karl Pearson’s Correlation(r). Results: In 15-28 weeks, all parameters had nearly equal r-values. Among all parameters, TCD revealed highest correlation with value of 0.997. In 29-40 weeks, there was considerable difference in r-values. An r-value of 0.982 was noted, when the GA by TCD and LMP was compared, r-value of which is more than the other parameters. The least correlation was seen with BPD, r=0.951. The second most accurate correlation was seen with the FL with r-value of 0.981. Conclusion: TCD is an accurate parameter in estimation of gestational age in second and third trimesters as its values are in close relation with that of GA by LMP. It is also better predictor of the gestational age when compared to other parameters especially in third trimester.

AB - Introduction: The most important parameter needed for appropriate management of pregnant women is accurate Gestational Age (GA). Routine sonographic estimation of GA by using Biparietal Diameter (BPD), Femur Length (FL), Abdominal Circumference (AC) and Head Circumference (HC) assumed important role in management of pregnancy. However, these parameters have limitations. BPD and HC are not reliable in case of moulding of foetal head in third trimester. Similarly, femur length is shortened in cases of achondroplasia. Transcerebellar Diameter (TCD) was developed as an alternative parameter of foetal brain growth and for estimation of GA. Aim: To evaluate accuracy of predicting GA using Foetal Transcerebellar Diameter (TCD) and to compare between TCD and other existing parameters in evaluating GA in 15 to 40 weeks of gestation. Materials and Methods: A prospective study was carried out in 100 pregnant women between 15 to 40 weeks of gestation, who came for routine antenatal sonography. Transcerebellar diameter was measured along with routine parameters. Subjects were divided into two groups based on GA (15-28 and 29-40 weeks). Gestational age using TCD and other parameters was calculated and compared with gestational age based on Last Menstrual Period (LMP). Correlation between the GA by LMP with GA by other ultrasound parameters was done by using Karl Pearson’s Correlation(r). Results: In 15-28 weeks, all parameters had nearly equal r-values. Among all parameters, TCD revealed highest correlation with value of 0.997. In 29-40 weeks, there was considerable difference in r-values. An r-value of 0.982 was noted, when the GA by TCD and LMP was compared, r-value of which is more than the other parameters. The least correlation was seen with BPD, r=0.951. The second most accurate correlation was seen with the FL with r-value of 0.981. Conclusion: TCD is an accurate parameter in estimation of gestational age in second and third trimesters as its values are in close relation with that of GA by LMP. It is also better predictor of the gestational age when compared to other parameters especially in third trimester.

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